降钙素原在肺癌细菌性肺炎患者诊断中的应用  

Application of procalcitonin in diagnosis of bacterial pneumonia in lung cancer patients

作　　者：邹洪兴[1] 周虹[1] 

机构地区：[1]浙江省嘉兴市第一医院检验科,浙江嘉兴314000

出　　处：《中国卫生检验杂志》2012年第5期1110-1111,1115,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:研究血清降钙素原(PCT)在肺癌细菌性肺炎患者诊断中的实用价值。方法:回顾性研究肺癌并发肺部感染患者86例,根据肺部感染的病原体诊断标准分为细菌性肺炎组(54例)和非细菌性肺炎组(32例),检测并比较两组PCT和C反应蛋白(CRP)值,将两组数据进行统计学比较。结果:肺癌细菌性肺炎组患者血清中PCT水平高于非细菌性肺炎组,差异具有统计学意义(P<0.05),CRP水平与非细菌性肺炎组比较差异无统计学意义(P>0.05)。比较54例肺癌细菌性肺炎组患者血清中PCT增高例数和CRP增高例数,差异有统计学意义(P<0.05),PCT和CRP两个指标诊断细菌性肺炎不存在一致性。结论:PCT对肺癌患者是否并发肺部细菌感染具有明显的临床诊断价值。Objective：To evaluate the practical value of procalcitonin（PCT）in diagnosis of bacterial pneumonia in lung cancer patients.Methods： A total of 86 lung cancer patients with a complication of pneumonia were reviewed.According to the diagnostic criteria of pathogens of pneumonia,54 patients were enrolled in bacterial pneumonia group and 32 patients in non-bacterial pneumonia group.The PCT level and the C-reactive protein（CRP）level of the two groups were determined and compared with each other.Results： There was significant difference in PCT level between bacterial pneumonia patients and non-bacterial pneumonia patients group（P〈0.05）.The difference in CRP level between bacterial pneumonia patients and non-bacterial pneumonia patients group was not significant（P〈0.05）.There was significant difference between the higher level rate of PCT and CRP in 54 lung cancer patients with bacterial pneumonia（P〈0.05）,and the two indicators were not associated with each other for diagnosing bacterial pneumonia.Conclusion： Monitoring the PCT level in lung cancer patients would have an obvious clinical significance for finding bacterial pneumonia.

关 键 词：降钙素原 肺癌 细菌性肺炎 C反应蛋白 

分 类 号：R734.2[医药卫生—肿瘤]