结直肠癌术后肝转移39例临床分析  

Hepatic metastases of colorectal cancer post-operation:39 cases report

作　　者：张新生[1] 陈鑫[1] 任双义[1] 

机构地区：[1]大连医科大学附属第二医院普外科,辽宁大连116027

出　　处：《大连医科大学学报》2012年第3期281-283,共3页Journal of Dalian Medical University

摘　　要：[目的]分析结直肠癌术后肝转移病例临床资料,以提高诊治水平和预防措施。[方法]回顾性分析39例结直肠癌术后肝转移的病例临床资料,并比较不同治疗措施的疗效及肿瘤标记物水平。[结果]手术联合肝动脉灌注化疗栓塞患者中位生存时间长(27个月),无治疗相关并发症。有32例患者的CEA水平较发生肝转移前或者原发肿瘤手术后都明显升高;有29例CA19-9升高。[结论]肝转移灶外科切除联合肝动脉灌注化疗栓塞术是理想的治疗手段;介入化疗具有并发症少,全身影响小,疗效较好等优点;结直肠癌术后定期复查,尤其是CEA、CA19-9等指标,对早期诊断有一定价值。[ Objective] To improve the diagnosis and treatment liver metastasis colorectal cancer. [ Methods~ Thirty- nine cases suffering from hepatic metastases of colorectal cancer post - operation were analyzed retrospectively. Observed and compared curative effect of patients undergoing different therapeutic measures. [ Results ] The median survival time of patient undergoing surgical resection combined chemoembolization was the longest, 27 months （4 -48 m）, in addition, there was not complication. Tumor marker： CEA increased： 32 cases; CA19 -9 increased： 29 cases. ~ Conclusion] Sur- gical resection combined chemoembolization is the best therapeutic measure. Compared to chemotherapy, the local and sys- temic complication of chemoembolization was less, and the effects turn out to be a good outcome. Regular follow - up plays an important role in preventing the hepatic metastasis of colorectal cancer. Especially, CEA, CA19 -9 and other tumor markers has some value or was the key factor for early diagnosis.

关 键 词：结直肠癌 肝转移 术后 化疗栓塞术 

分 类 号：R735.3[医药卫生—肿瘤]