颈动脉重度狭窄伴MCI老年患者支架植入术后认知功能变化研究  

Study on cognitive function change in MCI senile patients with severe CAS after carotid artery stenting

作　　者：巴华君[1] 陆川[1] 孙军[1] 

机构地区：[1]浙江省温州市第二人民医院神经外科脑血管病介入诊治中心,浙江温州325000

出　　处：《医学影像学杂志》2012年第5期718-720,共3页Journal of Medical Imaging

基　　金：温州市科学技术局:温州市2010年第四期科技计划项目(经费自筹)中的项目(编号:Y20100314)

摘　　要：目的了解颈动脉重度狭窄伴MCI(mild cognitive impairment,轻度认知功能障碍)老年患者,经过颈动脉支架植入术治疗后认知功能的变化。方法应用蒙特利尔认知评估量表对32例患者在行颈动脉支架植入术前及术后1、3、6个月进行认知功能评估,并利用统计学分析对各时间点MoCA分值组间进行对比研究。结果支架植入治疗后随访的1、3及6个月,MoCA评分较术前明显提高;而且随着随访时间延长,MoCA评分有上升趋势;MoCA分值的提高有显著的统计学意义。结论颈动脉支架植入术可以使老年MCI伴颈内动脉起始段重度狭窄患者短期内的认知功能得到较大程度的改善。Objective To find out the change of cognitive function in the MCI senile patients with severe internal carotid artery stenosis after carotid artery stenting. Methods Total 32 MCI senile patients with severe internal carotid artery stenosis were treated with carotid artery stenting. All the patients were examined with MoCA before treatment and 1, 3 and 6 months after treatment. We utilized statistical analysis to contrast and analyze the every time group MoCA scores. Re- sults After treatment of 1, 3 and 6 months, the scores of MoCA were elevated significantly. The longer the follow-up time the higher the MoCA score in these group. The elevation of MoCA was statistic. Conclusion The carotid artery stenting can improve cognitive function in the MCI senile patients with severe internal carotid artery stenosis during shortterm follow-up.

关 键 词：轻度认知功能障碍 老年患者 颈动脉狭窄 重度 支架植入术 

分 类 号：R743[医药卫生—神经病学与精神病学] R815[医药卫生—临床医学]