青霉素肌注后峰时手指血与静脉血药浓度差异的探讨  

Difference of the peak plasma concentration of penicillin in finger and venous blood

作　　者：黑毅[1] 崔东[1] 孙文胜 

机构地区：[1]广州军区广州总医院,广州510010

出　　处：《中国医院药学杂志》1990年第7期301-302,共2页Chinese Journal of Hospital Pharmacy

摘　　要：本文介绍采手指血用微生物法测定青霉素血药浓度。对16名病人肌注青霉素G 钾80万单位后约40min 采静脉血1 ml,同步取手指血20～30 μl,测定青霉素的血药浓度。经初步实验证明,这两种方法测定结果没有显著差异(P>0.05).The plasma concentrations of penicillin G in finger blood were determined bymicrobioassay,and compared it with venous blood concentrations after penicillinG administration(800,000 u im)40 min in sixteen patients.Our results indicatedthe two methods did not have significant difference(p>0.05).It is conceivable todetermine penicillin concentrations in finger blood with careful procedure.

关 键 词：青霉素 手指血 静脉血 血药浓度 

分 类 号：R914.1[医药卫生—药物化学]