AIDS合并巨细胞病毒性视网膜炎的观察  

Cytomegalovirus retinitis associated with acquired immunodeficiency syndrome

作　　者：邵玲[1] 杜敏[1] 闫淑[1] 姚学云[1] 

机构地区：[1]郑州市第二人民医院眼科,郑州450006

出　　处：《中国实用眼科杂志》2012年第6期721-723,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨获得性免疫缺陷综合征（AIDS）合并巨细胞病毒（CMV）性视网膜炎患者的眼底改变特点及眼底荧光血管造影特征。方法已诊断为CMV性视网膜炎的AIDS患者共34例49只眼，进行常规视力、裂隙灯检查、眼底检查及荧光素眼底血管造影（FFA）检查，分析其眼底病变的临床特征。结果29只眼视网膜上见大片融合性黄白色坏死灶，边界不清，伴视网膜出血及血管炎改变；FFA晚期病灶区域弥漫性荧光素渗漏。12只眼周边部视网膜颗粒状坏死灶，边界欠清，未见明显视网膜出血、渗出及血管管壁改变；FFA显示病灶区域强荧光，晚期荧光素渗漏。4只眼视网膜前见大片灰白色增殖膜；4只眼继发视网膜脱离。结论CMV性视网膜炎主要表现为进行性坏死性的视网膜炎，伴出血及血管炎。Objective To investigate the fundus characteristics and fundus fluorescence angiogra- phy （FFA） features of cytomegalovirus （CMV） retinitis associated with acquired immunodeficiency syndrome （AIDS）. Methods Visual acuity, fundus features and fundus fluorescence angiography （FFA） were analyzed on 34 patients （49 eyes） with CMV retinitis. Results Representative CMV reti- nitis was characterized by full thickness, yellow-white, confluent granular retinal necrosis with hemor- rhage, vessel sclerotic and attenuated in 29 eyes. FFA showed fluorescein leakage in late phase. Un- representative CMV retinitis was demonstratedin 12 eyes, recognized as granular retinal necrosis lo- cated in peripheral retina. Hemorrhage and effusion was not obvious. Pre-retina membrane was found in 4 eyes and retinal detachment in 4 eyes. Conclusions CMV retinitis has a distinctive mani-festation with thickness, yellow-white retinal lesions, hemorrhage and retinal vasculitis.

关 键 词：获得性免疫缺陷综合征 巨细胞病毒性视网膜炎 眼底荧光血管造影 

分 类 号：R774.11[医药卫生—眼科]