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机构地区:[1]安徽省合肥市第三人民医院病理科,安徽合肥230022
出 处:《安徽医药》2012年第6期801-803,共3页Anhui Medical and Pharmaceutical Journal
摘 要:目的探讨Burkitt淋巴瘤的临床、病理特点及可能的病因。方法分析1例扁桃体Burkitt淋巴瘤的临床及病理资料,并结合文献复习。结果肿瘤细胞弥漫分布,中等大小、相对单一,星空图像可见,核分裂象多见。免疫组化:CD20+,CD10+,PAX5+,Bcl-6+,MuM1-,Bcl-2-,C-Myc消化过度,Ki-67+(约100%)。结论对Burkitt淋巴瘤的诊断需结合镜下图像及免疫组化,必要时进行基因重排。Objective To investigate the clinical, pathological characteristics and possible causes of Burkitt lymphoma( BL ). Methods Clinic-pathological data of one case of BL were analyzed. Combined with literatcure review. Results The tumor cells had diffused distribution with medium-size and relatively homogeneous character, much nuclear divisions were seen. "Sky" image was visible. Immuno- histochemistry showed : CD20 + , CD10 + , PAX5 + , Bcl-6 + , MuMl - , Bcl-2 - , and the positive rates of Ki-67 were about 100%, C-Myc protein was digested excessively. Conclusion The diagnosis of Burkitt lymphoma should be combined with the microscopic images and immunohistochemistry,and gene rearrangement was in need when necessary.
关 键 词:BURKITT淋巴瘤 免疫组化
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