低危人群中乳腺癌与人工流产相关关系的研究  

Breast Cancer and Induced Abortion in a Low risk population,

作　　者：简洁 李艺 张宏伟[2] 卜黎明[2] 

机构地区：[1]黑龙江省哈尔滨市香坊区卫生防疫站,哈尔滨150030 [2]黑龙江省哈尔滨医科大学公卫学院

出　　处：《预防医学情报杂志》2000年第1期16-19,共4页Journal of Preventive Medicine Information

摘　　要：目的　探讨人工流产与乳腺癌发病危险性之间的关系。方法　研究对象为经产妇女。资料以条件Logis tic回归模型分析。结果　乳腺癌患者 ( 2 3 2 )比对照妇女采用人工流产的机率高 ,分别为 60 8%和 4 1 3 %。经调整配对变量 ,教育程度 ,及初产年龄 ,采用过人工流产的妇女患乳腺癌的危险性比对照高 2 9(RR =2 9)倍 ,95 %CI为 1 4～ 4 4 ( 95 %CI =1 4～ 4 4 )。而在低于 3 5岁的妇女中 ,其相对危险度为 4 5 ,95 %CI为 1 9～10 7(RR =4 5 ,95 %CI=1 9～ 10 7) ,高于 3 5岁以上的妇女的相对危险度 ,RR为 2 4 ,95 %CI为 1 5～ 3 9(RR =2 4 ,95 %CI =1 5～ 3 9)。Objective a case-control study of breast cancer was condueted in the women aged under 45 to investigate the relationship of induced abortion to subsequent breast cancer risk.Methods The study was restricted to parous women.Analyses were conducted using conditional logistic regression.Results The women with breast cancer(n=232) were more likely to have the abortion (60 8%) than the control women(41 3%).The risk of breast cancer in the women who had experienced the abortion, adjusted for the matching variables,education,and age at the first delivery was 2 9 times greater than that of other women(95%CI=1 4～4 4) The risk of breast cancer was somewhat higher among the women at age 35 years or less(RR=4 5,95%CI=1 9～10 7) than that of the older women (RR=2 4,95%CI=1 5～3 9).Conclusion The study of breast cancer in a population at low risk supports the hypothesis of that induced abortion may increase the risk of breast cancer in women.

关 键 词：乳腺癌 人工流产 相关关系 研究 

分 类 号：R737.902[医药卫生—肿瘤] R169.42[医药卫生—临床医学]