五元氮杂环苯丙烯酸及其类似物的合成  

Synthesis of Five-Membered Nitrogen-Containing Heterocycle Cinnamic Acid and its Analogues

作　　者：叶文峰[1] 袁明[1] 李家明[1] 何勇[1] 周鹏[1] 

机构地区：[1]安徽中医学院药学院,安徽省现代中药重点实验室,安徽合肥230031

出　　处：《广州化工》2012年第11期89-91,100,共4页GuangZhou Chemical Industry

基　　金：安徽省高校自然基金重点项目(批准号:KJ2010A206)

摘　　要：以芳酸酯为起始原料,经过一系列反应,合成了2个三氮唑芳酸醚类衍生物,2个咪唑芳酸醚衍生物,所合成的目标化合物未见文献报道,其结构均经1H-NMR、13C-NMR、MS确证,所设计的合成技术简单易行。Two triazole aromatic acid ether derivatives and two imidazole aromatic acid ether derivatives were synthe- sized. The target compounds were synthesized from aryl esters via a series of reactions. Two triazole aromatic acid ether derivatives and two imidazole aromatic acid ether derivatives were synthesized and they went reported in literatures. The chemical structures were confirmed by IR, 1H-NMR, ~3C -NMR and MS. The synthesis technology designed was sim- ple.

关 键 词：三氮唑 咪唑 化学合成 结构表征 

分 类 号：R914[医药卫生—药物化学]