血清超敏C反应蛋白检测在胃良恶性溃疡鉴别诊断中的应用  

The role of serum high-sensitivity C-reactive protein(hs-CRP) in benign and malignant gastric ulcer

作　　者：喻文强[1] 黄赞松[1] 周喜汉[1] 

机构地区：[1]广西右江民族医学院附属医院消化内科,广西百色533000

出　　处：《临床和实验医学杂志》2012年第11期848-849,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨血清超敏C反应蛋白(hs-CRP)在胃良、恶性溃疡诊断及鉴别诊断中的意义。方法应用免疫荧光法测定59例胃良性溃疡患者、72例胃恶性溃疡患者及63例健康人血清hs-CRP浓度。结果胃良、恶性溃疡组血清hs-CRP浓度水平明显高于健康对照组血清hs-CRP水平(P<0.01);且恶性溃疡组hs-CRP水平高于良性溃疡组(P<0.01)。结论血清hs-CRP在胃恶性溃疡中明显升高,对胃良、恶性溃疡的鉴别诊断有一定的临床价值。Objective To explore the significance of serum concentration of hs - CRP in the diagnosis and differential diagnosis of benign and malignant gastric ulcer. Methods Serum hs - ClIP concentration was detected in 59 cases of benign gastric ulcer,72 cases of malignant gastric ulcer and 63 healthy people by immunofiuorescence assay. Results Mean serum hs - CPtP levels in benign and malignant gastric ulcer group were significantly higher than that in normal control group （ P 〈0.01 ）, and mean serum hs - CRP level in malignant gastric ulcer group was higher than that in benign gastric ulcer group （ P 〈 0.01 ）. Conclusion Serum hs - CRP level in the patients with malignant gastric ulcer is significantly higher, and it may contribute to discrimination of the benign and malignant gastric ulcer.

关 键 词：超敏C反应蛋白 胃溃疡 胃癌 

分 类 号：R730.4[医药卫生—肿瘤] R573.1[医药卫生—临床医学]