Maddrey判别函数与酒精性肝病预后评估  

Maddrey's discriminant function and evaluation of prognosis in alcoholic liver disease

作　　者：杨洪波[1] 

机构地区：[1]四川省泸州市人民医院消化内科,四川泸州646000

出　　处：《中国当代医药》2012年第16期38-39,共2页China Modern Medicine

摘　　要：目的探讨Maddrey判别函数在酒精性肝病预后评估中的应用。方法将酒精性肝病患者分为轻、中、重度组,比较各组患者的Maddrey函数评分,比较各组患者30d后的预后与Maddrey判别函数评分的关系。结果酒精性肝病患者的Maddrey判别函数评分随病情加重而增加(P<0.05),死亡组的Maddrey判别函数评分显著高于非死亡组(P<0.05)。结论在酒精性肝病患者,Maddrey判别函数在其病情与预后评估方面具有重要意义。Objective To explore the predicting utility of Maddrey＇s discriminant function in alcoholic liver disease（ALD）.Methods Patients with ALD were divided into mild group,moderate group and severe group.Score of Maddrey＇s discriminant function was observed in each group.Relationship between Maddrey＇s discriminant function score and prognosis of short term mortality was evaluated in patients with ALD after 30 days.Results Score of Maddrey＇s discriminant function had relationship with pathogenetic condition in patients with ALD（P 0.05）.As compared with the patients in non-died group,higher score of Maddrey＇s discriminant function was observed in the patients of died group（P 0.05）.Conclusion It is useful for Maddrey＇s discriminant function to estimate the pathogenetic condition and prognosis in alcoholic liver disease.

关 键 词：酒精性肝病 Maddrey判别函数 预后 评估 

分 类 号：R575[医药卫生—消化系统]