中国树鼩下丘脑视上核和室旁核催产素能神经元的形态和神经纤维的分布  

Morphology of the OT-ergic Neurons in the SON and the PVN of the Hypothalamus of the Tupaia Belangeri Chinensis and Distribution of Their Nerve Fibres

作　　者：刘能保[1] 张敏海[1] 刘少纯[1] 李宏莲[1] 戴晓莉[1] RBock 周顺长[1] 

机构地区：[1]同济医科大学基础医学院组织胚胎学教研室,武汉430030 [2]德国萨尔州大学解剖学研究所,洪堡萨尔66421

出　　处：《同济医科大学学报》2000年第1期40-42,共3页Acta Universitatis Medicinae Tongji

基　　金：德国大众汽车公司基金!(China-Programm-Az.1/63663)

摘　　要：为了证实中国树鼩下丘脑视上核和室旁核内催产素（ｏｘｙｔｏｃｉｎ， ＯＴ）能神经元的形态和神经维在神经垂体内的分布，采用ＡＢＣ免疫组织化学技术进行了观察。结果发现，在各核团内，ＯＴ能胞体均散在分布，大多呈圆形或卵圆形，少数呈梭形或星形。核圆形，大多偏心位。免疫反应产物弥散分布于胞浆内。分布在正中隆起（ＭＥ）和垂体神经部内的ＯＴ能神经纤维直径微细，数目少，免疫反应性弱，但有数目较多，体积较大且大小不等的ＯＴ免疫反应凝聚体和赫令体。提示中国树鼩ＯＴ能的与加压素（ＶＰ）能的胞体及神经纤维免疫反应性存在差异。Using ABC-immunohistochemical technique, the morphology of the oxytocin (OT)-ergic neurons in the supraoptic (SON) and the paraventricular nuclei (PVN) of the hypothalamus in Tupaia belangeri chinensis and distribution of their OT-ergic fibres in neurohypophysis were demonstrated. The results were as follows: The OT-ergic perikarya were scattered in the SON and PVN. The great majority of them were rounded or ovoid, and the minority fusiform or starry in contour. The nucleus of the OT-ergic neuron were spherical and the majority eccentrically located. The immunoreactive products were diffusely distributed in the cytoplasm. The OT-ergic nerve fibres distributed in the median eminence (ME) and the pars nervosa were thin in diameter and few in number. The OT-immunoreactivities were weak in intensity. But there wers OT-immunoreactive concretions and Herring bodies which were more in number and greater in volume in the ME and the pars nervosa, respectively. These results suggested that there were differences between OT-ergic perikaya and vasopressin (VP)-ergic one in the immunoreactivities and distribution of the nerve fibres.

关 键 词：神经元 催产素 视上核 室旁核 下丘脑 树QU 

分 类 号：R322.8[医药卫生—人体解剖和组织胚胎学]