幽门螺杆菌尿素酶抗体检测幽门螺杆菌感染  

Urease antibody test in detection of helicobacter pylori infection

作　　者：钱坤艳 帅小博 陆静娴[2] 陈宇翔[3] 

机构地区：[1]江苏省南通市崇川区疾病预防控制中心,江苏南通226001 [2]南通大学附属医院,江苏南通226001 [3]江苏省南通市第一人民医院,江苏南通226001

出　　处：《中国卫生检验杂志》2012年第6期1352-1353,1356,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:探讨幽门螺杆菌尿素酶抗体检测幽门螺杆菌感染。方法:以组织切片染色法及快速尿素酶法联合检测结果作为幽门螺杆菌感染诊断"金标准",对110份公共场所从业人员检测幽门螺杆菌尿素酶抗体并与"金标准"进行对比分析。结果:尿素酶抗体检测幽门螺杆菌感染敏感性、特异性、准确性及阴阳性预测值分别为94.6%、95.2%、94.8%、87.0%及98.1%;公共场所从业人员现症感染总阳性率为38.2%,不同性别、年龄及不同行业间差异不明显。结论:幽门螺杆菌尿素酶抗体检测是检测幽门螺杆菌感染较理想的方法。Objective：To discuss the values of Helicobacter pylori urease antibody test in detection of infection of Helicobacter pylori.Methods：Using combined detection results of histological staining test and rapid urease test as the gold standards,110 Helicobacter pylori urease antibodies from public place jobholders were analyzed and compared with the gold standards.Results：The diagnosis sensitivity,specificity,accuracy and the negative and positive predictive value of Helicobacter pylori urease antibody test were 94.6%,95.2%,94.8%,87.0% and 98.1% respectively.The total positive rate of Helicobacter pylori infection in public place jobholders was 38.2%,and there was no statistics difference in different genders,ages and vocations.Conclusion：The Helicobacter pylori urease antibody test can be used as a reliable and prompt method for diagnosis of Helicobacter pylori infection.

关 键 词：幽门螺杆菌 尿素酶抗体 公共场所 从业人员 

分 类 号：R573.6[医药卫生—消化系统]