超微粉碎对丹参提取物质量影响研究  

Research on Super-micro Grinding of Salvia and the Quality Influences of Salvia Extract

作　　者：郑行林[1] 罗森[2] 袁崇均[2] 王笳[2] 陈帅[2] 吴燕[2] 

机构地区：[1]成都中医药大学附属医院药剂科,四川成都610072 [2]四川省中医药科学院,四川成都610041

出　　处：《四川中医》2012年第6期59-60,共2页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:研究超微粉碎技术与传统提取方法对丹参提取物质量的影响。方法:以重金属、有害元素及丹参酮ⅡA、丹酚酸B为指标,用药典方法及HPLC法进行分析测定,以比较丹参饮片、粗粉、细粉及超微粉对重金属、有害元素及丹参酮ⅡA、丹酚酸B含量的影响。结果:丹参超微粉碎对成分提取率明显高于饮片及粗粉,而重金属及有害元素符合药典规定。结论:超微粉碎技术工艺可提高丹参中成分的提取率,但应注意对重金属及有害元素的检测。Objective： Study on super-micro grinding technology and traditional extraction methods and the quality of salvia extract. Methods： Heavy metal, harmful elements and tanshinone IIA, salvianolic acid B were as an index, Pharmacopoeia method and HPLC were the test methods, comparing salvia crude slices, coarse powder, grinding powder and super-micro grinding powder on the content differences of heavy metal, harmful elements, tanshinone IIA and salvianolic acid B. Results ： Super-micro grinding of salvia on extraction rate was significantly higher than crude slices and coarse powder, and heavy metal and harmful el- ements were in keeping with the pharmacopoeia. Conclusion： Technology of super-micro grinding process can improve the salvia extraction rate, but should pay attention to detect heavy metal and harmful elements.

关 键 词：丹参提取物 超微粉碎 丹参酮ⅡA 丹酚酸B 高效相色谱法 

分 类 号：R284.2[医药卫生—中药学]