ⅠA期非小细胞肺癌冷冻消融疗效分析  

Cryotherapy ablation for StageⅠA non-small cell lung cancer

作　　者：马旭阳[1] 肖越勇[1] 吴斌[1] 张肖[1] 刘士榕[1] 任超[1] 

机构地区：[1]解放军总医院放射科,北京100853

出　　处：《中华临床医师杂志（电子版）》2012年第12期101-104,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的观察CT引导下氩氦刀冷冻消融治疗ⅠA期非小细胞肺癌的可行性、并发症及疗效。方法经医院伦理委员会批准2008年6月至2009年11月接受氩氦刀冷冻治疗的ⅠA期非小细胞肺癌患者29例,其中男24例,女5例,平均年龄(62.1±7.4)岁,包括细支气管肺泡癌(BAC)3例,腺癌17例,鳞癌9例,经术后6、12、24个月随访观察,统计原位肿瘤复发、生长情况。结果所有患者均未出现严重并发症;29例患者中,术后6个月复查时可见2例患者肿瘤组织灭活不完全,病灶保持相对稳定,其后复查中发现病灶处于进展状态;其余27例患者6个月内原位未见肿瘤组织生长,其后随访过程中发现3例患者出现纵隔淋巴结转移;3例患者出现远处转移;21例患者经术后2年随访,未见肿瘤复发或转移征象。结论氩氦刀冷冻治疗能有效灭活肿瘤,且安全性高,值得临床推广。Objective To investigate the therapeutic effect and complications of CT-guided percutaneous cryoablation for Stage I A non small cell lung carcinoma（NSCLC）. Methods From June 2008 to November 2009, 29 cases of Stage I A NSCLC were treated by percutaneous cryoablation. All the patients were followed-up for 24 months after the operation, using contrast-enhanced CT to evaluate the tumor size and enhancement. Results There was no serious complications occurred;follow-up in the 6th month showed that 2 lesions show SD, others show CR. In 24 months, 3 patients were found lymph node of mediastinal enlarged. 3 patients were found metastasis,21 patients show CR. Conclusions CT-guided percutaneous cryoablation is a simple, safe and reliable procedure for NSCLC with the maximum diameter less than 3 cm.

关 键 词：肺肿瘤 冷冻疗法 体层摄影术 X线计算机 

分 类 号：R734.2[医药卫生—肿瘤]