^(99)Tc^m-MIBI显像在口腔颌面部肿块中的诊断价值  

Evaluation of Clinical Value of ^(99)Tc^m-MIBI SPECT in Diagnosis of Masses in Maxillofacial Region

作　　者：刘洪伟[1] 李贵昌[1] 

机构地区：[1]济宁市第一人民医院口腔颌面部外科,山东济宁272100

出　　处：《口腔医学研究》2012年第6期547-549,共3页Journal of Oral Science Research

摘　　要：目的:探讨99 Tcm-MIBI放射性核素显像在口腔颌面部肿块术前定性诊断的价值。方法:对64例口腔颌面部肿块患者术前行放射性核素显像,显像剂为99 Tcm-MIBI,所有病例均行早期和延期显像以判断肿块性质。定性分析行卡方检验,病变侧与颈部肌肉放射性摄取比值(T/N)行t检验,判断结果与病理诊断相比较。结果:99 Tcm-MIBI显像对口腔颌面部肿块诊断的灵敏度、特异性和准确性分别为68.00%、89.74%和81.25%,39例颌面部良性肿块阴性35例(89.74%),假阳性4例(10.26%);25例颌面部恶性肿块阳性17例(68.00%),假阴性8例(32.00%);定性分析卡方检验差异有统计学意义。口腔颌面部良恶性肿块T/N,早期相分别为1.53±0.42,1.90±0.38,经t检验两者差别有统计学意义(t=4.352,P<0.01);延期相分别为1.43±0.61,1.99±0.45,经t检验两者差别有统计学意义(t=3.959,P<0.01)。结论:99 Tcm-MIBI显像可作为鉴别口腔颌面部良恶性肿块的一种检查方法,腮腺区肿块的鉴别优于颌面部其他部位肿块。Objective：To evaluate the clinical value of 99Tcm-MIBI SPECT on classifying maxillofacial masses as benign or malignant before treatment.Methods：SPECT images of the maxillofacial region were obtained in 64 patients with maxillofacial masses before surgery.We used 99 Tcm-MIBI as imaging agent.All the patients were evaluated by early and delay 99 Tcm-MIBI imaging.The chi-square test was used to compare date statistically of maxillofacial masses.The results were compared with their pathological diagnoses,clinical examination.Results：The sensitivity,specificity and accuracy of 99 Tcm-MIBI SPECT imaging in determining maxillofacial masses were 68.00%,89.74%,81.25%respectively.35 of 39 patients who had benign tumors showed negative images（89.74%）,4 patients showed positive images（10.26%）;17 of 25 patients who had malignant tumors showed positive images（68.00%）,8 patient showed negative image（32.00%）,and there was a significant difference between the two groups by chi-square test.The early uptake ratios of benign and malignant maxillofacial masses were respectively1.53±0.42,1.90±0.38（t=4.352,P〈0.01）;the delay uptake ratios of maxillofacial masses were respectively1.43±0.61,1.99±0.45（t=3.959,P〈0.01）.Conclusion：It could be considered as a routine method to classify maxillofacial masses.Diagnosis of parotid gland masses were better than the other areas of maxillofacial masses.

关 键 词：颌面部肿块 放射性同位素 体层摄影术 MIBI 

分 类 号：R739.8[医药卫生—肿瘤]