新型含紫罗兰酮基查尔酮的合成与表征  

Synthesis and Characterization of Ionone-containing Chalcones

作　　者：刘长辉[1] 文瑞明[1] 叶晓琴[1] 易先文[1] 方磊[1] 

机构地区：[1]湖南城市学院化学与环境工程系,益阳413000

出　　处：《应用化学》2012年第7期780-783,共4页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金资助项目(51074069);湖南省科技计划项目(2010GK3161);益阳市科技计划项目(2011JZ36)

摘　　要：在碳酸钠和氢氧化钠催化下,β-紫罗兰酮和5,6-环氧-β-紫罗兰酮与芳香醛于室温下研磨1～15 min,制备了8种新型含紫罗兰酮基查尔酮,其结构经1H NMR、MS、IR和元素分析表征。结果表明,β-紫罗兰酮、苯甲醛、Na2CO3与NaOH的物质的量比为20∶20∶5∶15时,收率可达87.1%～94.8%,苯甲醛环上吸电子基团可促进反应进行。Condensation of β-ionone and 5,6-epoxyl-β-ionone with aromatic aldehydes by sodium carbonate and sodium hydroxide was carried out to afford eight novel ionone-containing chalcones at room temperature for 1 - 15 min by grinding, and their structures were characterized by ^1H NMR, MS, IR and elemental analysis. The effeets of substituents, the types and amounts of catalysts on the reaction were studied. The results show that the yield is 87. 1% - 94. 8% when the molar ratio ofβ-ionone, benzalaldehyde, sodium carbonate and sodium hydroxide is 20： 20： 5： 15, and electron withdrawing group promotes the condensation.

关 键 词：查尔酮 Β-紫罗兰酮 环氧-β-紫罗兰酮 缩合反应 合成 

分 类 号：O625.4[理学—有机化学]