虾青素胶囊治疗膝关节骨性关节炎疗效观察  

Clinical observation on Astaxanthin capsula in the treatment of osteoarthritis of knee joint

作　　者：裴凌鹏[1] 白岩[1] 郑玲玲[1] 张万强[2] 朱嘉[2] 李莉[2] 

机构地区：[1]国家民委-教育部少数民族传统医学重点实验室,北京100081 [2]中国中医科学院望京医院,北京100070

出　　处：《中国临床新医学》2012年第6期483-485,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：中央民族大学2009-2010年度自主科研计划资助项目(编号:0910KYCZ01);教育部"长江学者和创新团队发展计划"资助项目(编号:IRT0871)

摘　　要：目的观察虾青素胶囊治疗膝关节骨性关节炎的疗效。方法将60例膝关节骨性关节炎患者随机分为治疗组(30例)和对照组(30例)。治疗组给予虾青素胶囊治疗,对照组给予芬必得治疗。比较两组治疗前后膝关节功能评分,观察主要症状缓解情况和治疗效果。结果 (1)治疗组的疼痛缓解持续时间较对照组缩短,而疼痛缓解时间较对照组延长(P均<0.01);(2)两组治疗后关节功能较治疗前均有提高(P均<0.01),而治疗组比对照组更优(P<0.05);(3)总有效率治疗组为66.67%,对照组为83.33%,两组疗效比较差异无统计学意义(P>0.05)。结论虾青素胶囊治疗骨性关节炎有一定的疗效。Objective To observe the effect of Astaxanthin capsula in the treatment of knee osteoarthritis. Methods Sixty patients were randomly divided into treatment group and control group, treatment group received Astaxanthin capsula （1 capsules ,2 times daily） ,the control group received Finbid （400 rag,2 times daily ）, for 60 days. Results The total effective rate of treatment group and control group were 66. 67% and 83.33%. Compared with the control group, the difference was statistically significant （ P 〉 0.05 ）. The pain relief time was longer and the maintenance time of pain relief was shorter after treatment （ all P 〈 0.01 ）. After treatment, the knee function in two groups were improved （ all P 〈 0.01 ） ; the treatment group was superior to the control group in improvement of knee function （ P 〈 0. 05 ）. Conclusion Astaxanthin capsula in the treatment of knee osteoarthritis shows better efficacy.

关 键 词：膝关节骨性关节炎 疗效观察 治疗组 虾青素 胶囊 治疗前后 疼痛缓解 对照组 

分 类 号：R863.42[医药卫生—临床医学]