吸毒人群血清ACTH、5-HT、β-内啡肽和cAMP水平的研究  

A CLINICAL RESEARCH ON LEVELS OF ACTH,5-HT,β-ENDORPHIN,cAMP ANDOTHER PARAMETERS OF DRUG ADDICTS

作　　者：杨朝阳[1] 李灿东[1] 黄世庚 吕京和 

机构地区：[1]福建中医药大学,福州350108 [2]福建省司法厅劳教局,福州350003

出　　处：《中国药物依赖性杂志》2012年第3期200-201,共2页Chinese Journal of Drug Dependence

基　　金：国家自然科学基金(30973718);福建省自然基金项目(2009J01174)

摘　　要：目的:研究吸毒人群血清ACTH、5-羟色胺(5-HT)、β-内啡肽和cAMP水平与健康人群的差异。方法:对吸毒者和健康者进行病例-对照研究,吸毒者诊断标准均符合《中国精神障碍分类与诊断标准》第三版(CCMD-3)。结果:吸毒组与健康组血清cAMP水平存在显著性差异;5-HT、ACTH、β-内啡肽水平在两组间无显著性差异。结论:吸毒人群血清cAMP的含量升高可能是影响情志改变的因素之一。Objective：To compare the levels of serum ACTH,5-HT,β-endorphin,cAMP among drug addicts and control subjects.Methods：The cases-control comparison between drug addicts and healthy people was adopted.Diagnosis standards of drug addicts conform to the standards in Chinese Classification of Mental Disorders,CCMD-3.Results：There is a significant difference in cAMP level between drug addict group and healthy group;while no differences in 5-HT,ACTH,β-endorphin between two groups were observed.Conclusion：The increased serum cAMP may be one of the factors that influence the emotion changes in drug addicts.

关 键 词：吸毒 促肾上腺皮质激素 5-羟色胺 Β-内啡肽 环磷酸腺苷 

分 类 号：R745.42[医药卫生—神经病学与精神病学]