耳穴贴压联合强阿片类药物治疗中、重度癌痛50例疗效观察  

Clinical Observation on Auricular Acupressure Therapy Combined with Strong Opioids for Moderate to Severe Cancer Pain

作　　者：钟敏钰[1] 胡作为[1] 黄琳[1] 但丹[1] 成薇婷[1] 

机构地区：[1]武汉市第一医院

出　　处：《中医杂志》2012年第13期1123-1125,共3页Journal of Traditional Chinese Medicine

摘　　要：目的观察耳穴压豆在中、重度癌痛治疗中的减毒增效作用。方法将100例中、重度癌痛患者随机分为两组,每组50例,对照组予奥施康定口服治疗,治疗组在对照组基础上给予耳穴压豆,7天后观察两组镇痛缓解率、用药剂量及恶心、呕吐、便秘的发生率和程度。结果两组各程度疼痛镇痛率比较,差异均无统计学意义(P>0.05);两组各程度疼痛镇痛药用量比较,治疗组少于对照组(P<0.05);治疗组恶心、呕吐及便秘总发生率低于对照组,差异有统计学意义(P<0.05)。结论耳穴压豆联合强阿片类药物治疗中、重度癌痛临床确切,并能减少阿片类药物用量,有效降低消化系统毒副反应。Objective To observe the attenuation and synergy effects of auricular acupressure therapy for moderate to severe cancer pain. Methods One hundred cases of moderate to severe cancer pain were randomized into treatment group and control group, with 50 in each. The control group was given Oxycontin orally and the treatment group was combined with the auricular aeupressure therapy. The analgesic response rate, dosage and the incidence and extent of nausea, vomiting and constipation of both groups were observed 7 days later. Results There was no significant difference in the analgesic response rate between groups （P〉0.05）. The dosage of Oxycontin in the treatment group was significantly lower than that in the control group （P〈 0.05）. The incidence of nausea, vomiting and constipation in the treatment group was significantly lower than that in the control group （P〈0.05）. Conclusion The auricular aeupressure therapy combined with strong opioids is effective for moderate to severe cancer pain, especially in reducing the dosage of strong opioids and digestive toxicity.

关 键 词：耳穴贴压 癌性疼痛 恶心 呕吐 便秘 奥施康定 

分 类 号：R730.5[医药卫生—肿瘤]