性别因素在孤独症发病中的作用(综述)  

Role of sex differences in pathogenesis of autism:A review

作　　者：徐新杰[1] 张嵘[1] 

机构地区：[1]北京大学神经科学研究所,北京大学基础医学院神经生物学系,神经科学教育部重点实验室,卫生部神经科学重点实验室,北京100191

出　　处：《中国心理卫生杂志》2012年第6期455-459,共5页Chinese Mental Health Journal

基　　金：国家自然科学基金(30973832)

摘　　要：孤独症是一类病因未明的广泛性发育障碍性疾病,男性孤独症患病率明显高于女性,且患者大脑、心理和行为常表现出一定的极端雄性化倾向。本文对性别差异与孤独症发病的相关理论和研究进展进行了简要概述,并分析了性激素影响孤独症发病可能机制,希望能够对孤独症的预防和诊疗提供帮助。Autism is a pervasive developmental disorder with an unexplained etiology, and the prevalence of autism is strongly biased towards males. The brain, psychology and behaviors of patients also show kind of extreme masculinization. In this paper, theories and researches related to sex differences and autism were summarized and the effect of sex hormones on the pathogenesis of autism and its possible mechanisms were analyzed.

关 键 词：性激素 孤独症 社交障碍 综述 

分 类 号：R749.94[医药卫生—神经病学与精神病学]