内镜下结晶紫染色结合病理活检对提高Barrett食管诊断准确率及其肠化型检出率的研究  

By the Crystal Voilet's Fluid Staining Under Endoscopy United with Pathological Findings to Increase the Accuracy Rate of Barrett's Esophagus(BE) and Detection Rate of Intestinal Mataplasia BE

作　　者：孙敬平[1] 樊元春[1] 

机构地区：[1]成都医学院第一附属医院消化内科,成都610500

出　　处：《临床消化病杂志》2012年第3期149-150,共2页Chinese Journal of Clinical Gastroenterology

基　　金：四川省卫生厅课题(090120)

摘　　要：目的通过内镜下结晶紫染色结合病理活检提高对Barrett食管(BE)的诊断准确率及肠化型BE检出率。方法选择我院近两年166例经内镜检查疑诊为BE病变的患者为研究对象,随机分为常规内镜组和色素内镜组。常规内镜组采取内镜检查结合病理活检的方法。色素内镜组先用0.05%结晶紫染色液进行染色,根据染后黏膜变化选择病理活检部位,比较两组的准确率和肠化型BE的检出率。结果色素内镜组BE的诊断准确率为86.42%,肠化型BE的检出率为27.16%;常规内镜组分别为64.70%和10.59%,两组比较有显著差异性。结论内镜下结晶紫染色结合病理活检诊断BE的方法和传统的普通内镜结合病理活检比较,其诊断准确率和肠化型BE的检出率明显提高,是一种简单、实用的检查方法,值得推广。Objective To increase the accuracy rate of Barrett＇ s esophagus （BE） and detection rate of intestinal mata- plasia BE（IM-BE） by the crystal voilet＇s fluid staining under endoscopy united with pathological findings. Methods 166 ca- ses suspected as BE were divided into two groups randomly. One is the ordinary endoscope group and the other is the pigment endoscope group. In the ordinary endoscope group, the endoscopy together with biopsy was taken from. In the pigment endoscope group, the affectcd part was dyed with 0.05% crystal voilet＇ s fluid,and then after 1 to 2 minutes,the biopsy was taken from the affections through dying,then comparison was made with histopathologic findings. Results The rate of accuracy and detec- tion of IM-BE in pigment endoscope group were 86.42% and 27.16% , respectively while in the ordinary endoscope group, they were 64.70% and 10.59%. Thus there was noticeable difference between the two groups. Conclusion The cystal voilet＇s fluid pigment endoscope has a better accuracy rate in the diagnosis of BE, and also have a higher decteetion rate in the IM-BE, therefore it is an uncomplicated and practical examination.

关 键 词：BARRETT食管 结晶紫染色 肠化型BE 

分 类 号：R571[医药卫生—消化系统]