综合性医院门诊质子泵抑制剂合理用药情况分析  

Analysis on Reasonable Application of Proton Pump Inhibitors for Outpatients in General Hospital

作　　者：姚苏宁[1] 严小惠[1] 

机构地区：[1]宁波卫生职业技术学院 宁波市全科医学教育培训中心,浙江省宁波市315100

出　　处：《中国全科医学》2012年第16期1882-1884,共3页Chinese General Practice

基　　金：浙江省社会科学界联合会研究课题(2011Z21)

摘　　要：目的了解某综合性医院质子泵抑制剂(proton pump inhibitors,PPIs)门诊用药情况,促进临床合理用药。方法采用随机数字表法随机抽取2010年6月—2011年5月含PPIs的处方1 442张,从剂量、时间、超药典应用、合并用药情况等方面,分析其使用的合理性。结果 PPIs用药处方总体合理,但不合理用药或不完全合理应用处方128张,不合理率为8.9%。结论 PPIs存在过度使用,临床上宜权衡利弊,合理应用。Objective To investigate the medication of proton pump inhibitors （PPIs） for outpatients in a genera hos- pital so as to promote the rational clinical use of PPIs. Methods The random number table method was taken to select 1 442 pre- scriptions containing PPIs for outpatients in hospital from June 2010 to May 2011. The rationality of PPIs use was analyzed in terms of dosage, timing, application beyond pharmacopoeia, and combined medication. Results The medications of PPIs were generally reasonable. However, there were 128 prescriptions that were irrational or not completely rationale, with irrationality ra- tio of 8.9%. Conclusion Tliere exists a condition of over administering PPIs, so how to balance the pros and cons clinically is important for applying PPIs reasonably.

关 键 词：质子泵抑制剂 合理用药 处方分析 

分 类 号：R969.3[医药卫生—药理学]