小梁切除术联合丝裂霉素C治疗难治性先天性青光眼的临床观察  

Study on mitomycin-C-augmented trabeculectomy in refractory congenital glaucoma

作　　者：杨巧玲 陈卫东 郝红燕 

机构地区：[1]河北省保定市第二医院眼科,071000

出　　处：《眼科新进展》2000年第2期121-123,共3页Recent Advances in Ophthalmology

摘　　要：目的　证实在先天性青光眼常规手术失败的儿童小梁切除术联合丝裂霉素 C(mitomycin- C,MMC)治疗是安全有效的方法。方法　 9例 (9眼 )曾行常规手术失败的先天性青光眼儿童在小梁切除术中一次应用 MMC棉片 (0 .2 g· L- 1 )置于手术创面 5 min,平均随访时间 17.6 4mo± 8.41mo(0 .2 5～ 36 mo)。结果　术前平均眼压 4.0 0± 0 .6 3k Pa(3.0 7～4.93k Pa) ,术后平均眼压 1.83± 0 .10 k Pa(1.38～ 2 .0 3k Pa) ,均保持了术前的视力水平 ,成功率 88.89% (8眼 )。基本成功率 11.11% (1眼 )。常见并发症浅前房 8眼 (88.89% )。结论　小梁切除术联合 MMC治疗在常规手术失败的先天性青光眼儿童是安全有效的方法。Objective To investigate and determine the safety and effect of mitomycin C augmented trabeculectomy on children with refractory congenital glaucoma who failed to recover conventional surgeries.Methods Mitomycin C augmented(0.2g·L -1 for 5 minutes)trabeculectomies were used in charts of 9 eyes of 9 patients during conrentional congenital glaucomal surgeries.Results The mean follow up was 17.64months±8.41 months(range 0.25~36 months).The mean intraocular pressure(IOP)was reduced from 0.40kPa±0 63kPa(range 3.07~4.93kPa)before the surgery to the postoperative level of 0.23kPa±0.10 kPa(range 1.41~2.03kPa).Visual acuities after the surgeries were nearly kept at the same levels as the pre operative ones in all patients.A complete success, record was achieved in 8 eyes(88.89%).Only one eye(11.11%)was classified as a qualified success' record.The common complication as shallow anterior chambers occurred in 8 eyes.Conclusion Mitomycin C augmented trabeculectomy is safe and effective on children with failed traditional trabeculectomy surgeries.

关 键 词：先天性青光眼 小梁切除术 丝裂霉素C 

分 类 号：R775.405[医药卫生—眼科]