VEGF在脑星形细胞瘤中的表达与64排CT征象的关系  

Correlation of 64-slices CT Features with Vascular Endothelial Growth Factor Expression in Brain Astrocytoma

作　　者：蔡胜艳[1] 孙妍[1] 胡嘉航[1] 

机构地区：[1]牡丹江医学院红旗医院放射科,黑龙江牡丹江150001

出　　处：《医疗卫生装备》2012年第6期67-68,共2页Chinese Medical Equipment Journal

摘　　要：目的:探讨脑星形细胞瘤64排CT征象与VEGF表达之间的关系。方法:搜集经手术证实的脑星形细胞瘤30例,分析其CT表现,术后对肿瘤组织标本进行免疫组化染色,分析其VEGF表达的程度与CT征象之间的关系。结果:星形细胞瘤的VEGF表达程度与肿瘤的分级、瘤周水肿的范围及肿瘤的强化程度有相关性。结论:星形细胞瘤的CT表现可以反映VEGF的表达程度,能对临床治疗方案的选择和患者预后的评估起到重要作用。Objective To study the correlation of 64-slices CT features with vascular endothelial growth factor（VEGF） expression in brain astrocytoma.Methods CT findings in 30 cases with surgically and pathologically proved astrocytoma were retrospectively analyzed.VEGF was stained with immuno-histochemical technique,and VEGF expression levels were compared with CTfeatures.Results VEGF expression levels were well correlated with pathological grade,the extent of per tumor edema and the degree of contrast enhancement.Conclusion CT features of astrocytoma can reflect VEGF expression levels.It is important for the choice of clinical treatment and prognostic evaluation of patients.[Chinese Medical Equipment Journal,2012,33（6）：67-68]

关 键 词：VEGF 64排CT征象 脑星形细胞瘤 

分 类 号：R739.4[医药卫生—肿瘤]