中国老年男性快速步速与认知的相关性  

Association of rapid gait speed with cognition in Chinese male elder

作　　者：陈大伟[1] 杜文津[1] 靳雁斌[1] 刘玮[1] 陈晋文[1] 李华军[1] 

机构地区：[1]空军总医院干部病房,北京100142

出　　处：《中国临床保健杂志》2012年第3期225-227,共3页Chinese Journal of Clinical Healthcare

基　　金：空军总医院年度计划课题资助项目(KZ2010019)

摘　　要：目的分析中国老年男性快速步速与认知功能的相关性。方法以160名空军驻京离退休老干部作为研究对象,对其进行快速6 m行走和简易精神状态检查量表(MMSE)的测试,通过体检报告和电子病例档案收集社会人口学和慢性疾病等信息。结果 Logistic回归显示,经性别、年龄及与MMSE相关的教育、慢性心力衰竭和既往卒中等因素的调整后,快速步速与认知功能异常(MMSE≤24)具有显著相关性(P=0.002),OR值为0.751(0.625～0.902)。根据快速步速评分区分认知功能异常的ROC曲线下面积为0.805(0.739～0.872)(P<0.01)。结论中国老年男性快速步速与认知功能关系密切,并能较好反映受者认知功能的水平和区分认知功能异常者。Objective To study the association of rapid gait speed with cognition in Chinese male elder subjects. Methods A coross-sectional survey was carried out in the 160 retired cadres of Air Force PLA. 6-meter rapid walking and mini-mental status examination （MMSE） were tested for them. The demographics and chronic diseases were collected from their entire report of health examination and electric record of case history. Results In Logistic regression models, after controlling for sex, age, and education levels, chronic heart failure, pre-stroke which are associated with MMSE, rapid gait speed had a significant association （ P = 0. 009） with cognitive impairment （ MMSE ≤24） ,and the OR was 0. 751 （0. 625 ≤0. 902,P 〈 0.01 ）. The area under receiver-operator characteristic （ROC） curve for rapid gait speed to discriminate the cognitive impairment was 0. 805 （0.739 ≤ 0.872, P 〈 0.01 ）. Conclusion Rapid gait speed is significantly associated with cognition in Chinese male elders, and thus is a useful maker for discriminating the cognitive level.

关 键 词：步行 认知 ROC曲线 老年人 男(雄)性 

分 类 号：R749.1[医药卫生—神经病学与精神病学]