脑出血动物血液及胃液中神经降压素变化的动态观察  

Dynamic monitoring of neurotensin in blood and gastric juice of animal with cerebral hemorrhage

作　　者：李亚洁[1] 翟惠敏[2] 黄健美[3] 唐亚莉 王春慧 石向群[3] 

机构地区：[1]第一军医大学南方医院护理部,广东广州510515 [2]第一军医大学护理系,广东广州510515 [3]第一军医大学南方医院神经内科,广东广州510515

出　　处：《第一军医大学学报》2000年第2期156-157,173,共3页Journal of First Military Medical University

基　　金：广东省自然科学基金!(98016)

摘　　要：目的研究脑出血与神经降压素变化的相关性，以利于判断急性颅脑损伤的预后和进行营养护理。方法动态观察以脑出血动物模型脑出血不同时期以及进食前后血浆和胃液神经降压素（ＮＴ）含量的变化。结果发现在动物急性脑损伤初期，血浆中ＮＴ浓度增高，病情稳定后，ＮＴ含量逐渐恢复正常：进食后血浆和胃液中ＮＴ明显升高（与空腹时相比有显著性差异）。结论神经降压素变化与颅脑损伤有密切相关性。神经降压素的释放受进食的影响。Objective To study the relationship between cerebral hemorrhage and the change in the level of neurotensin (NT) for the purpose of making prognoctic judgement of acute cerebral injury and optimizing nutritional nursing care for the patients. Methods Cerebral hemorrhage animal model was established in dogs to observe the changes of NT content in plasma and gastric juice preprandially and postprandially after the injury, Results in the initial stages of cerebral injury, the concentration of NT in plasma increased, but recovered the normal level gradually when the condition was brought to stability. Postprandially, NT can be released into blood circulation and manifest hormonal property. Conclusion Changes in NT level are closely related with cerebral hemorrhage. Lipid plays an important role in the stimulation of NT secretion, in the process of which amino acid and glucose take no part,

关 键 词：神经降压素 狗 脑出血 

分 类 号：R743.3[医药卫生—神经病学与精神病学]