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机构地区:[1]广西壮族自治区妇幼保健院儿童医院优生遗传科,南宁530003
出 处:《中国优生与遗传杂志》2012年第7期94-95,共2页Chinese Journal of Birth Health & Heredity
摘 要:目的掌握本地区新生儿及婴幼儿TORCH感染情况及特点,为临床诊断及治疗提供依据。方法采用酶联免疫吸附试验检测患儿血清TORCH-IgM抗体,比较新生与婴幼儿抗体阳性率。结果 5920例患者中,TORCH-IgM阳性率为6.01%,新生儿和婴幼儿阳性率分别为3.40%和19.58%,以CMV阳性为主,且婴幼儿阳性率高于新生儿(P<0.01)。TORCH-IgM阳性患儿主要临床表现为肝炎综合征、病理性黄疸和肺炎。结论南宁地区新生儿及婴幼儿TORCH感染率较高,以CMV感染为主,且缺乏特异临床表现;加强高危人群TORCH筛查是降低出生缺陷发生率和减少患儿后遗症的有效措施,这对优生优育、提高人口素质具有重要意义。Objective : To investigate the prevalence and characteristic of the TORCH infection in Neonates and Infants, and provide basis for clinical diagnosis and treatment. Methods : TORCH - IgM antibody were detected by using enzyme linked immunosorbent assay method in the serum. Results: Among the 5920 cases, the overall infection rate of TORCH was 6.01% , and that were 3.40% and 19. 58% in group of Neonates and Infants respectively. CMV was main pathogens, and the positive rate of TORCH -IgM in Neonates was higher than that in Infants. Hepatitis syndrome, pathological jaundice and pneumonia were the main clinical manifestations among the positive cases of TORCH - IgM. Conclusion : The positive rate of TORCH in Neonates and Infants was high in Nanning. the specific clinical manifestations of TORCH infection was lack. The surveillance of TORCH Infection should be performed among high - risk groups.
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