肝炎肝硬化患者血浆神经肽Y水平初步观察  

The Primary Observation On The Level of Plasma Neuropeptide Y In Hepatic Cirrhosis

作　　者：刘锦堂[1] 王培珍[1] 孔宪牛[1] 高峰[1] 

机构地区：[1]山东省临沂市人民医院,山东276003

出　　处：《临床肝胆病杂志》2000年第2期96-97,共2页Journal of Clinical Hepatology

摘　　要：为观察肝炎肝硬化患者的血浆神经肽Y水平 ,采用放射免疫法检测了 5 6例肝炎肝硬化患者血浆神经肽Y浓度。结果显示 ,所测患者神经肽Y浓度均高于正常人 ,差异有显著性 (P <0 0 5～ 0 0 1)。伴有腹水者显著高于无腹水者 ,腹水经治疗消失后 ,神经肽Y浓度下降 ,但仍高于正常人 ;神经肽Y血浆水平与肝功能分级亦有相关性 。WT5”BZ]To observe the levels of plasma neuropeptide Y(NPY) in hepatic cirrhosis(HC),Radio-immunoassay was used to detect the plasma NPY level in 56 patients with HC Results:plasma NPY levels were greatly higher in HC patients than in healthy people[(179 67+40 22)ng/L vs (132 19+25 07)ng/L],and plasma NPY levels were increased when hepatisis became more severe,and they were higher in the patients with ascites than in those without ascites NPY may be involved in the pathogenesis of HC,and plasma NPY levels might be taken as a prognostic marker in patients with HC [WT5”HZ]

关 键 词：肝炎肝硬化 神经肽Y 放射免疫测定 

分 类 号：R575[医药卫生—消化系统]