消化道早期癌肿内镜黏膜下剥离术  

Endoscopic submucosal dissection for gastrointestinalearly stage cancer

作　　者：吴义先[1] 李敏[1] 汪文生[1] 

机构地区：[1]安徽医科大学附属安庆医院消化内科,安徽安庆246003

出　　处：《安徽医药》2012年第7期979-981,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨消化道早期癌肿内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)治疗的临床疗效。方法对该院近2年消化道早期癌肿的住院患者12例行ESD,术中观察其并发症,术后进行内镜及病理随访。结果 12例患者均一次性完整切除病灶。手术时间为55～148 min,平均时间101.5 min。其中发生术中出血10例,均内镜下成功止血,未发生术后迟发出血;术中穿孔1例,经金属夹夹闭后内科保守治疗治愈。所有病例均术后随访,随访6个月创面均完全愈合,随访期为6～24个月(平均15个月),未见病变残留及复发。结论 ESD是一种安全有效的治疗方法,可提高整块切除率,减少病灶残留及复发,根治性切除早期消化道癌肿。Objective To explore the clinical effect of endoscopic submucosal dissection for gastrointestinal early stage cancer. Methods Endoscopic submucosal dissection was performed on 12 cases of gastrointestinal early stage cancer in Anqing Hospital Affiliated to Anhui Medical University in the past two years. The complication in operation was observed,followed up with endoscopic or endoscopic ultrasonography after ESD. Results Twelve cases of gastrointestinal early stage cancer were dissected successfully through endoscopy. The operative time was between 55 to 148 minutes with all the average of 101.5 minutes. Intraoperative bleeding occurred in 10 cases,which was controlled successfully by endoscopy. There was no delayed postoperative hemorrhage. Perforation occurred in one patient during the procedure, and was closed with endoclips without surgical treatment. All cases of gastrointestinal early stage cancer were followed up after ESD for 6 to 24 months, and the average was 15 months, and all healed with no residue or recurrence. Conclusion ESD is a safe and ef- fective treatment method, which improves the complete resection rate, reduces the residual and recurrent lesions and achieves the goal of radical resection for gastrointestinal early stage cancer.

关 键 词：早期癌肿 胃肠道肿瘤 内镜黏膜下剥离术 

分 类 号：R735[医药卫生—肿瘤]