移动条野技术的放射生物学和剂量学基础及改进  

Radiation biology and dosimetry of moving strip technique

作　　者：夏云飞[1] 钱剑扬[1] 郑作深[2] 

机构地区：[1]中山医科大学肿瘤防治中心放疗科,广东广州510060 [2]广东省江门市中心医院肿瘤科,广东江门529070

出　　处：《癌症》2000年第1期82-85,96,共5页Chinese Journal of Cancer

基　　金：广东省重点科技攻关项目!(粤科字[1996]46号)

摘　　要：目的：阐明常规移动条独特的优点及其局限性，并对其进行改进。方法：从放射生物学方面包括时间剂量因子、分次剂量因子和体积剂量因子等三个方面及从剂量学方面分析了移动条野照射技术，针对其局限性，引进了由靶区长度每次剂量，总剂量和疗程时间决定的照射野宽度与每次移动距离的计算模型。结果：移动条野照射技术在一定条件下能提高肿瘤的生物效应，同时减少正常组织的反应。结论：移动条野照射技术有其本身的适应证和应用价值。Objective: To demonstrate advantages and limits of regular moving strip technique and to improve this technique. Methods: Moving strip technique was analyzed from the aspects of biology, including time-dose effect, fractionation-dose effect, volume-dose effect, and its dosimetry. As for the limits of the moving strip technique, the calculated model was put forward according to length of target volume, width of irradiation field derived from fractionation dose, total dose and total time of radiation treatment, and width of strip. Results: This technique can enhance biological effect of radiation against tumor and alleviate toxicity reaction of normal tissue in given cases. Conclusion: Moving strip technique has itself indications and still has value to be used in radiation oncology.

关 键 词：移动条野技术 肿瘤 放射疗法 放射生物学 剂量 

分 类 号：R730.55[医药卫生—肿瘤]