B超引导下冷循环微波刀治疗晚期肝癌82例疗效分析  

B ultrasound-guided cryocycle microwave for advanced liver cancer: a report of 82 cases

作　　者：周任[1] 

机构地区：[1]广西省玉林市第一人民医院肝胆外科,广西玉林537000

出　　处：《中国普通外科杂志》2012年第7期801-803,共3页China Journal of General Surgery

摘　　要：目的:探讨B超引导下冷循环微波刀辅助治疗晚期肝癌的临床效果。方法:164例晚期肝癌患者根据入院顺序随机分为研究组与对照组,各82例。两组首先都采用栓塞治疗,研究组在此基础上加用B超引导下冷循环微波刀治疗。结果:研究组完全缓解12例,部分缓解40例,稳定10例,进展20例,总有效率为63.4%(52/82);对照组中完全缓解8例,部分缓解22例,稳定22例,进展30例,总有效率为36.6%(30/82),研究组疗效优于对照组,两组总有效率比较差异有统计学意义(χ2=5.760,P<0.05)。研究组灭活率为97.6%,对照组灭活率为81.7%,差异有统计学意义(χ2=6.852,P<0.05)。所有患者在治疗后当天均出现上腹部疼痛,均未作特殊处理后消失,无1例术后出现胃肠穿孔等严重并发症。结论:B超引导下冷循环微波刀联合栓塞治疗晚期肝癌安全、有效、实用,值得推广应用。Objective： To investigate the efficacy of B ultrasound-guided cryocycle microwave in adjuvant therapy for advanced liver cancer. Methods： One hundred and sixty-four consecutive patients with advanced liver cancer were randomly allocated either to study group or control group,with 82 cases in each group.Patients in both groups underwent embolization therapy,and then the patients in study group received,additionally,the B ultrasound-guided cryocycle microwave treatment. Results： Of the patients in study group,complete response was achieved in 12 cases,partial response was obtained in 40,stable disease was seen in 10 cases,progressive disease occurred in 20 cases,and overall response rate was 63.4%（52/82）,while these parameters in control group occurred in 8,22,22,30 cases and 36.6%（30/82）,respectively.The efficacy in study group was better than that in control group and the overall rates between the two groups had statistical significance（χ2=5.760,P0.05）.The tumor deactivation rate was 97.6% in study group and 81.7% in control group,and the difference had statistical significance（χ2=6.852,P0.05）.All the patients had abdominal pain on the day after treatment,which disappeared without further special treatment,and no serious complications such as gastrointestinal perforation occurred in any of the patients. Conclusion： B ultrasound-guided cryocycle microwave combined with embolization therapy for advanced liver cancer is safe,effective and applicable,and deserves to be widely used.

关 键 词：肝肿瘤/外科学 冷循环微波 超声检查 化学栓塞 治疗性 

分 类 号：R735.7[医药卫生—肿瘤]