肢体缺血预处理缓解缺血再灌注损伤的研究进展  

Recent advances in the relieving effect of limb ischemic preconditioning against ischemia-reperfusion injury

作　　者：蒋高霞[1] 徐桂华[1] 孟娣娟[1] 

机构地区：[1]南京中医药大学外科教研室,江苏南京210046

出　　处：《中国普通外科杂志》2012年第7期877-880,共4页China Journal of General Surgery

基　　金：江苏省高校自然科学基金项目(10KJB320011)

摘　　要：缺血再灌注损伤是外科手术中比较常见的问题,大量的研究证实肢体缺血预处理可以积极地缓解手术中引起的缺血再灌注损伤,有关肢体缺血预处理的相关研究逐步增多,笔者将肢体缺血预处理研究进相关进展进行综述,主要内容包括肢体缺血预处理所保护的靶器官和肢体缺血预处理的相关保护机制。Ischemia-reperfusion injury is often encountered in surgical practice.Numerous studies have shown that limb ischemic preconditioning（LIPC） can protect organs from ischemia-reperfusion injury during surgery.In view of the accumulating evidence of this phenomenon,this paper addresses the progresses associated with LIPC that include the LIPC target organs and their underlying protective mechanisms.

关 键 词：缺血预处理 肢体 再灌注损伤 综述文献 

分 类 号：R364.1[医药卫生—病理学]