扩散加权成像在胰腺癌与肿块型胰腺炎中的鉴别诊断价值  

The application of MR diffusion-weighted imaging in differentiating pancreatic carcinoma from mass-forming pancreatitis

作　　者：丁庆国[1] 陆志华[2] 贾传海[1] 陆永明[1] 王建[1] 

机构地区：[1]常熟市第二人民医院影像中心,江苏常熟215500 [2]常熟市第一人民医院影像中心

出　　处：《实用放射学杂志》2012年第7期1056-1058,1062,共4页Journal of Practical Radiology

摘　　要：目的探讨磁共振扩散加权成像（DWD）在胰腺癌与肿块型胰隙炎中的鉴别诊断价值。方法对胰腺癌组（n=17）、肿块型胰腺炎组（n=12）、正常对照组（n=25）均行磁共振常规扫描和DWI（b值取0．600s／mm^2），分析病变组织与正常胰腺DWI信号特点，并测定各组表观扩散系数值（ADC）。定量分析比较各组间ADC值有无统计学差异。结果胰腺癌组、肿块型胰腺炎组、对照组ADC值分别为（1．77±0．08）×10^-3mm^2／s、（1．97±0．17）×10^-3mm^2／s、（1．46±0．28）×10^-3mm^2／s，胰腺癌组ADC值低于肿块型胰腺炎组（t=5．71，P〈0．05）、低于对照组（t=5．34，P〈0．05），肿块型胰腺炎组ADC值高于对照组（t=5．13，P〈0．05）。结论DWI有助于胰腺癌与肿块型胰腺炎的鉴别诊断,可作为常规MRI的重要补充检查办法。Objective To investigate the value of MR diffusion weighted imaging（DWI）in differentiating pancreatic carcinoma from mass-forming pancreatitis . Methods 17 patients with pancreatic carcinoma （ group A ） , 12 cases with mass-forming pancrea titis （ group B ）and 25 normal volunteers （ group C ） underwent routine MRI and echo-planar DWI （EPI/DWI ） using b value of 0, 600 s/mm^2. Signal intensities on DWl were compared between three groups and apparent diffusion coefficient （ ADC ） values of three groups were calculated and qualitatively analyzed comparatively among groups . Results The ADC values were （ 1.77 ± 0.08 ） 10 ×10^-3mm^2/s,（1. 97±0. 17）×10^-3mm^2/s,（1.46±0. 28）×10^-3mm^2/s in group A,B and C, respectively. The ADC values of group A was lower than that of group B（t=5. 71,P〈0. 05） and group C（t=5. 34,P〈0. 05） ,respectively. TheADC values of group B was higher than that of group C（t=5.13,P〈0.05）. Conclusion DWI provides an important supplement to the routine MRI in differentiating pancreatic carcinoma from mass-forming pancreatitis.

关 键 词：胰腺 胰腺癌 胰腺炎 磁共振成像 

分 类 号：R735.9[医药卫生—肿瘤] R445.2[医药卫生—临床医学]