老年人大肠黑变病的临床和内镜特点分析  

Research on clinical and endoscopic features of Melanosis coli in aged people

作　　者：祁小鸣[1] 陈恕之[1] 周步良[1] 

机构地区：[1]南京医科大学第三附属医院消化内科,江苏仪征211900

出　　处：《胃肠病学和肝病学杂志》2012年第7期629-631,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨老年人大肠黑变病(Melanosis coli,MC)的病因及其临床和内镜特点。方法总结我院自2000年-2010年间电子结肠镜检查4 821例中发现60岁以上58例老年MC的临床资料,并进行回顾性分析。结果老年MC病变多累及1个或多个肠段,全结肠发病率较高,58例中25例伴有大肠息肉,其中大肠腺瘤23例,5例伴有结肠癌,便秘49例,服用泻药53例。结论老年MC的病因主要与便秘和长期服用蒽醌类泻药有关,其伴发大肠息肉和结肠癌几率增加。Objective To explore the causes, clinical and endoscopic features of Melanosis coli in aged people. Methods The clinical data of 58 aged patients with Melanosis eoli were found by video endoscopic examination in our hospital from 2000 to 2010 and were retrospectively analyzed. Results One or more colonic sections were involved in most aged Melanosis coli patients. The whole colon had a higher incidence rate. Among 58 cases, colonic polyps was detected in 25 cases, including 23 cases of colonic adenoma, 5 cases of colon carcinoma. 53 cases had constipation and 49 cases had history of using laxative. Conclusion The major causes of aged Melanosis coli are chronic constipation and taking anthraquinone laxatives for long time, the probability of melanosis coli with polyps and tumor increased.

关 键 词：老年人 大肠黑变病 便秘 蒽醌 

分 类 号：R574.6[医药卫生—消化系统]