不同功率He:Ne激光对种植体骨结合面积影响的动物实验研究  

Animal Study for Influence of Different Low-power Laser Irradiation on Osseointegration of Dental Implants

作　　者：范芹[1] 徐世同[2] 王宇彤 吕聪[4] 段瑞平 

机构地区：[1]遵义医学院附属口腔医院种植科,贵州遵义563003 [2]广东省口腔医院.南方医科大附属口腔医院 [3]海珠区第二人民医院 [4]遵义医学院 [5]昆明市口腔医院

出　　处：《口腔医学研究》2012年第7期629-631,共3页Journal of Oral Science Research

基　　金：广州市海珠区科技重点攻关项目(编号:2007-Y-005)

摘　　要：目的:探索不同功率He:Ne激光对种植体骨结合面积的影响。方法:选取成年雄性Beagle犬6只,每只犬每侧胫骨植入4枚种植体,种植体随机编入A、B、C、D组,A、B、C组为实验组,D组为对照组,每组12枚,共48枚。实验组术后立即采用不同功率He:Ne激光垂直照射种植体对应体表,A组15.9J/cm2、B组26.5J/cm2、C组37.1J/cm2,20min/次,1次/d,持续2周。术后1、2、3个月分别处死2只犬,取标本制作种植体骨磨片,Goldner’s三色法染色后测量种植体骨接触率,所得数据采用统计学处理。结果:种植体骨接触率:术后1、2个月A、B、C、D组间无显著差异,术后3个月A与B及C与D组间无显著差异,A、B组明显高于C、D组(P<0.05)。结论:术后持续照射低功率He:Ne激光2周,能明显增加种植体骨结合的面积,以15.9J/cm2或26.5J/cm2照射效果最佳。Objective： To explore the influence of different power laser irradiation on implant-osseointegration.Methods： 6 Beagle male dogs were selected.4 Implants were implanted in both sides of the tibia of each dog.The implants were randomly divided into group A,B,C,and D.There were totally 48 implants,with 12 for each group.A（15.9 J/cm2）、B（26.5 J/cm2）、C（37.1 J/cm2） groups as the experimental group were immediately irradiated after surgery,the time of irradiation was two weeks,20min /once,one time a day.Speinens were obtained 1,2,and 3 months after implantation,while two animals were put to death each time.16 tibial implant specimens were made,for the general observation and production of bone implants with grinding plate.After Goldner’s trichrome the bone-implant contact（BIC） was measured and analyzed.Results： About bone-implant contact（BIC） one and two months after operation the statistically significant difference was not found among four groups.Three months after operation the statistically significant difference was found between A,B and C,D groups（P〈0.05）,A,B groups were better than C,D groups.Conclusion： It was concluded that after two weeks’ irradiation the effect of 15.9 J/cm2 and 26.5 J/cm2 low-power on increasing final bone-implant contact and achieving implant-bone contact was better.

关 键 词：种植体 低功率激光 种植体-骨结合率 组织学 

分 类 号：R783.6[医药卫生—口腔医学]