1例胃癌患者术后辅助化疗的药学监护  

Pharmaceutical care on a gastric cancer patient treated with postoperative adjuvant chemotherapy

作　　者：宋鑫[1,2] 黄立峰[1] 

机构地区：[1]南京军区福州总医院药学科,福建福州350025 [2]解放军92医院药械科,福建南平353000

出　　处：《中国药物应用与监测》2012年第3期144-146,共3页Chinese Journal of Drug Application and Monitoring

摘　　要：通过阐述临床药师对1例胃恶性肿瘤化疗患者实施药学监护的过程,探讨临床药师如何做好化疗患者的药学监护工作。针对该病例化疗方案(多西他赛+氟尿嘧啶+亚叶酸钙)发生率较高的药物不良反应,及时地制定和应用药物预防方案,避免可能出现的胃肠道反应、过敏反应等化疗不良反应;对化疗过程中出现的骨髓抑制、感染等问题,结合患者病情,依据治疗指南及临床药学知识,与临床医师共同讨论和实施升白药物和抗菌药物的用药方案,根据疗效及时调整用药,使肿瘤患者顺利完成周期化疗。本文为临床药师在防治化疗药物不良反应方面实施合理有效的药学监护工作提供参考。The pharmaceutical care on a gastric cancer patient treated with chemotherapy was implemented and explored. Accounting for some adverse drug reactions of chemotherapy program （docetaxel ＋ fluorouracil ＋ calcium folinate） with higher incidence in the cases, the clinical pharmacist constituted and applied the drug prevention program in time to avoid possible gastrointestinal reactions, allergic reactions, etc. During chemotherapy, according to treatment guidelines and clinical pharmacy knowledge, leucocyte increasing agents and the anti-bacterial drug regimens were discussed to solve the adverse reactions, such as bone marrow suppression and infection. Then, the medication was timely adjusted based on the therapy efficacy. At last, the cancer patient successfully completed the cycle of chemotherapy. The prevention and treatment of adverse reactions induced by chemotherapy drugs could provide the reference for clinical pharmacists in reasonable and effective pharmaceutical care.

关 键 词：临床药师 药学监护 化疗 药品不良反应 

分 类 号：R735.2[医药卫生—肿瘤]