CT与MRI图像融合对脑转移瘤三维适形放疗靶区的影响  

The influence of target volume by CT/MRI image fusion on brain metastasis′s three-dimensional conformal radiotherapy

作　　者：陈苏玮[1] 袁锋[1] 林志仁[1] 王伟锋[1] 

机构地区：[1]海南省海口市人民医院肿瘤放疗科,海南海口570000

出　　处：《中国医药导报》2012年第20期75-76,共2页China Medical Herald

基　　金：海南省自然科学基金立项项目:辐射敏感元件介导的p53基因联合放疗对肿瘤细胞作用的研究(项目编号:310149)

摘　　要：目的研究CT与MRI图像融合的脑转移瘤靶区与CT图像靶区的不同,提高三维适形放疗靶区勾画的准确性。方法同期采集25例脑转移瘤患者的CT和MRI图像,传送至图像处理工作站融合成CT/MRI图像,分别在CT及CT/MRI融合图像勾画41组GTV,比较两种图像勾画的GTV的差别。结果 25例患者共41组靶区的GTVCT为(31.75±9.93)cm3,GTVCT/MRI为(28.92±8.25)cm3。41个对照组中,GTVCT<GTVCT/MRI为18个,GTVCT>GTVCT/MRI为23个。结论采用CT/MRI融合后图像勾画的脑转移瘤靶区精确度提高,更适合于三维立体适形放疗。Objective To improve the accuracy of delineating three-dimenslonal conformal radiotherapy target volume by comparing the difference between computed tomography（CT）/magnetic resonance imaging （MRI） image fusion on brain metastasis area and CT＇s target area. Methods CT＇s images and MRI＇s images collected from 25 cases with brain metastasis in the same period were transmitted to image processing workstation and fused into CT/MRI images, and then 41 pairs of gross tumor volume （GTV） were delineated in CT and CT/MRI, and finally difference was compared between the two group. Results The value of GTVcr in 41 pairs from 25 cases was （31.75±9.93） cm3 and in GTVCT/MRI was （28.92±8.25） cm3. Among 41 control groups, the number of the accuracy of GTVcr lower than that of GTVCT/MRI was 18, GTCCT higher than that of GTVCT/MRI was 23. Conclusion The improving accuracy of brain metastasis＇s target volume sketched by CT/MRI image fusion is more suitable for three-dimensional conformal radiotherapy.

关 键 词：CT/MRI图像融合 脑转移瘤 靶区勾画 

分 类 号：R739.41[医药卫生—肿瘤]