IMRT联合热疗治疗中晚期直肠癌临床研究  

Clinical study on intensity-modulated radiation therapy combined with thermotherapy in treating advanced rectum cancer

作　　者：王园园[1] 王义善[1] 杨柯[1] 胡蓉蓉[1] 杨桂青[1] 

机构地区：[1]解放军第107医院,山东烟台264002

出　　处：《现代中西医结合杂志》2012年第21期2296-2297,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：全军科技攻关计划基金资助项目(06G034)

摘　　要：目的观察适形调强放射治疗(IMRT)联合热疗治疗中晚期直肠癌的临床疗效。方法将60例中晚期直肠癌患者随机分为单纯IMRT组及IMRT联合热疗组,分别给予相应治疗,比较2组患者治疗后临床疗效。结果 IMRT联合热疗组的治疗有效率87%,单纯IMRT组63%,2组有效率比较有显著性差异(P<0.05);在ZPS评分改善方面,IMRT联合热疗组也优于单纯IMRT组,且差异具有统计学意义。结论 IMRT联合热疗能够更有效地控制中晚期直肠癌,值得临床推广应用。Objective It is to observe the clinical effect of intensity-modulated radiation therapy （IMRT） combined with thermotherapy in the treatment for advanced rectum cancer. Methods Sixty patients with advanced rectum cancer were random- ly divided into IMRT group and IMRT combined with thermotherapy group. After treatment, the differences of clinical effect between these two groups were evaluated. Results The therapeutic effect was 87% in IMRT combined with thermotherapy group, and that was 63% in IMRT group, there was significant difference between both groups （P 〈 0.05）. In the aspect of the improvement of ZPS scores, IMRT combined with thermotherapy group was also better than IMRT group only, there was significant difference between both groups （P 〈 0.05）. Conclusion IMRT combined with thermotherapy can control advanced rectum cancer better, and thus, it deserves popularize clinical application.

关 键 词：IMRT 热疗 中晚期直肠癌 

分 类 号：R735.37[医药卫生—肿瘤]