形态学处理在肿瘤体积测量中的可行性分析  

Tumor Volume Assessment by Morphological Image Processing-a Feasibility Analysis

作　　者：陈仰纯[1] 陈萍[1] 

机构地区：[1]广州医学院第一附属医院PET-CT中心,广东省广州市510230

出　　处：《医学理论与实践》2012年第14期1692-1693,1703,共3页The Journal of Medical Theory and Practice

摘　　要：目的:基于CT图像,通过形态学处理软件C半自动化测量模型容积并与真实容积比较,验证该软件的有效性。方法:7个中空模型容积介于1.93～64.75ml,灌满16.6%的甘露醇溶液后,固定在水桶底座,水桶灌满水后,采集CT图像,测量模型壁厚度、CT值,以及16.6%的甘露醇溶液、水与空气的CT值。设空气/水,水/模型壁,空气/模型壁界面的CT值阈值分别是-20HU,16HU,-900HU。根据模型壁厚度自适应测量模型容积,并计算测量相对误差。结果:这7个模型壁厚从0.6～3.5mm不等,壁CT值(58.1±5.2)～(116.8±4.7)HU。模型内16.6%甘露醇溶液CT值(47.8±4.6)HU,水桶内水CT值(-2.6±4.2)HU,空气CT值(-1 002.4±2.4)HU。7个模型容积测量值容积从2.15～68.40ml,测量相对误差(-2.0±9.0)%。结论:形态学处理软件C能够测量模型容积,其准确性受限于CT图像的空间分辨率。Objeetive：A morphological image processing software C was established to semi-automatic outline a tumor based on computed tomography （CT） for oncologist. Volumes of a set of tumor phantom were assessed by software C, compared with the true volumes of them to test the efficiency of it. Methods： Seven hollow models were filled with 16.6% mannitol, fixed on the bottom of a barrel filled with water. The set of models spanning from 1.93mi to 64. 75ml were scanned by CT（Discovery ST8,GE）. The hounsfield units （HU） of walls of models, 16. 6% mannitol, water,and air, and the thickness of models＇ wall were measured by Matlab 2007b （Mathworks Ins. USA）. -20HU, 16 HU, and --900HU were set as threshold value for air/water, water/wall of models, and air/wall of models. The volume of a model was computed by the total voxel number inside of the model multiplied by the volume of voxel. The relative error of a model was computed. Results：The thickness of models＇wall ranged from 0. 6mm to 3. 5ram. The HU of models＇ wall were ranged from （58. 1±5. 2） to （116. 8±4. 7）HU. The HU of 16. 6% mannitol, water, and air was （47. 8±4. 6）HU, （-2. 6±4. 2）HU and （-1 002±4-2. 4）HU, respectively. The volumes of these models measured were spanning from 2. 15ml to 68. 40ml. The relative error was （-2.0±9. 0）%,ranged from --16. 4% to 11. 4%. Conclusion：The software C could semi-automatically assess the volume of a model. The accuracy of assessment was limited by the resolution of CT images.

关 键 词：形态学处理 模型 容积 

分 类 号：R73[医药卫生—肿瘤]