血清肝细胞生长因子水平变化与肝病的相关性探讨  

The Correlation Analysis between Liver Cell Growth Factors and Liver Diseases

作　　者：王利丽[1] 张海燕[1] 

机构地区：[1]山东大学附属济南市中心医院医学实验诊断中心,山东济南250013

出　　处：《中国医学创新》2012年第20期21-22,共2页Medical Innovation of China

摘　　要：目的:评价血清中肝细胞生长因子(HGF)水平与肝硬化、肝癌和慢性肝炎的关系,探讨血清HGF水平作为肝脏疾病临床指标的价值。方法:采用固相酶联免疫吸附法(ELISA)检测血清中HGF的水平。结果:肝硬化患者的HGF水平显著高于正常对照组(P<0.01),肝癌(HCC)和慢性肝炎(CH)患者的HGF水平明显高于正常对照组(P<0.05)。结论:HGF水平检测可作为肝脏疾病临床诊断和治疗的有价值指标。Objective：To explore the correlations between liver cell growth factor（HGF） levels in serum and liver disease（liver cirrhosis,liver cancer,and chronic hepatitis）,to study the significance of HGF as a clinical index value for liver diseases.Method：ELISA method was used to detect the levels of HGF in serum.Result：The level of HGF in patients with liver cirrhosis was significantly higher than that in normal controls（P0.01）,and the levels of HGF in hepatocellular carcinoma（HCC） and chronic hepatitis（CH） patients were obviously higher than that in normal controls too（P0.05）.Conclusion：HGF level detection in serum can be used as a clinical value index for the diagnosis and treatment of liver diseases.

关 键 词：肝细胞生长因子 肝硬化 肝癌 慢性肝炎 

分 类 号：R575[医药卫生—消化系统] R735.7[医药卫生—内科学]