2008-2010年上海地区结肠癌常用细胞毒药物利用分析  

Utilization analysis of anti-colon-cancer drugs in Shanghai during 2008 - 2010

作　　者：陆冰[1] 陆国椿[1] 

机构地区：[1]复旦大学附属肿瘤医院药剂科,复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中国临床药学杂志》2012年第4期231-233,共3页Chinese Journal of Clinical Pharmacy

摘　　要：目的评估上海地区结肠癌常用细胞毒药物使用现状和趋势,为临床合理用药提供参考。方法采用回顾性方法分析2008-2010年上海地区119家医院结肠癌常用细胞毒药物的销售数量、金额、用药频度(DDDs)和限定日费用(DDC),进行药物利用分析。结果结肠癌常用化疗药物总体用量呈快速增长,品种使用显示出明显的变化趋势。卡培他滨、奥沙利铂和西妥昔单抗的用量逐年增长,其药品消耗金额年增长率2009年分别为35.18%、15.62%和23.43%,2010年分别为10.33%、4.90%和20.07%;其药品销售数量增长率2009年分别为103.4%、11.12%和23.73%,2010年分别为10.33%、8.20%和17.81%。结论 2008-2010年结肠癌常用细胞毒药物总体用量呈快速增长,品种使用显示出明显的变化趋势。AIM To assess the utilization status and trend of commonly used cytotoxic drugs for colon cancer in Shanghai and provide a reference for cilinical medication. METHODS The retrospective analysis in the respect of con- sumption sum, consumption quantity,DDDs and defined daily cost（DDC） was performed and the data was collected from 119 hospitals in Shanghai region during 2008 - 2010. RESULTS The amount of capecitabine, oxaliplatin and cetuximab increased year by year. The growth rates of consumption sum were 35.18%, 15.62% and 23.43% respectively in 2009, and 10.33%, 4.90% and 20.07% respectively in 2010. The growth rates of consumption quantity were 103.4%, 11.12% and 23.73% respectively in 2009, and 10.33%, 8.20% and 17.81% respectively in 2010. CON- CLUSION During 2008- 2010, the consumption of anti-colon-cancer drugs increased quickly accompanying significant changes in varieties..

关 键 词：结肠癌化疗药物 用药频度 限定日费用 

分 类 号：R735.34[医药卫生—肿瘤]