多形性腺癌并发皮肌炎1例并文献复习  

The relationship between pleomorphic adenocarcinoma and dermatomyositis(with a case report and review of the literatures)

作　　者：邓思斯[1] 李觅[2] 张甦琳[3] 刘邦华[3] 

机构地区：[1]华中科技大学同济医学院附属协和医院肿瘤中心,武汉430022 [2]华中科技大学同济医学院附属同济医院骨科 [3]华中科技大学同济医学院附属协和医院耳鼻咽喉科

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第15期687-689,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:提高对多形性腺癌的认识,其存在并发皮肌炎的可能,探讨2种疾病之间是否存在一定关系。方法:报告1例咽旁间隙多形性腺癌并发皮肌炎的患者。明确住院期间对这两种疾病的诊断及治疗方式。回顾相关临床文献,进行归纳和文献复习。结果:该患者行腮腺浅叶部分切除术治疗后,术后病检及免疫组织化学检查明确多形性腺癌诊断。同时皮肌炎病情有所好转。结论:多形性腺癌存在并发皮肌炎的可能,容易漏诊。两者在自身免疫机制上可能存在关系。Objective：The purpose of this article is to improve the understanding of complications of pleomror-phic adenocarcinoma, and the possibility of complicated with dermatomyositis. In order to explore whether there is a certain relationship between the two diseases. Method.. Reported one patient in our hospital with the diagnosis of pleomorphic adenocarcinoma complicated dermatomyositis, and clarified the diagnosis and treatment of these two diseases during hospitalization. Reviewed the latest clinical literature relevant to pleomorphic adenocarcinoma and dermatomyositis. Result： The patients underwent superficial parotidectomy treatment. The postoperation patholog-ic and immunohistochemical examination confirmed the diagnosis of pleomorphic adenocarcinoma. Dermatomyositis improved better after the operation. Conclusion：Pleomorphic adenocarcinoma has the possibility of complicated with dermatomyositis which may misdiagnosis in clinical practice. Summarize the latest diagnosis pr;gress of pleomor-phic adenocarcinoma and the surgical treatment of the tumor. Also discuss the standards of clinical diagnosis and treatment of dermatomyositis. Analysis there may be a relationship between the two diseases on autoimmune mechanism.

关 键 词：多形性腺癌 皮肌炎 

分 类 号：R739.63[医药卫生—肿瘤]