壳聚糖对白色念珠菌的抑菌研究  

Bacteriostasis Research of Effect of Chitosan on Candida Albicans

作　　者：王莹[1] 李大鹏[1] 

机构地区：[1]黑龙江八一农垦大学食品学院,黑龙江大庆163319

出　　处：《农产品加工（下）》2012年第7期52-54,共3页Farm Products Processing

基　　金：大庆市科学技术计划项目(SCX2008-003-2)

摘　　要：对壳聚糖抑制白色念珠菌活性进行研究,考察壳聚糖对真菌中白色念珠菌活性的主要影响因素(不同壳聚糖浓度、pH值、金属离子、醋酸浓度),对其进行正交试验,确定壳聚糖对白色念珠菌抑菌活性的最优条件。结果表明,最佳抑菌条件为:A1B3C1,即壳聚糖质量分数为0.05%,pH值4,醋酸体积分数为1.5%。抑菌活性的影响程度为:壳聚糖浓度>醋酸浓度>pH值。This article studies on chitosan inhibiting Candida albicans activity of chitosan against fungi, investigation of Candida albicans in the activity of the main influence factors （different Chitosan concentration, pH, concentration of metal ions, acetic acid） , the orthogonal test, to determine the effect of chitosan on Candida aiblcans bacteriostatic activity of optimal conditions. The experimental results show that the optimal conditions for the A1B3C1, antibacterial chitosan concentration is 0.05%, pH is 4, acetic acid in a concentration of 1.5%. The severity of antibacterial activity is chitosan concentration 〉 acetate concentration 〉 pH.

关 键 词：壳聚糖 真菌 白色念珠菌 抑菌活性 

分 类 号：R96[医药卫生—药理学]