围生期颅内静脉窦血栓形成15例分析  

ANALYSIS OF 15 CASES WITH PERINATAL CEREBRAL VENOUS SINUS THROMBOSIS

作　　者：郭雪箐[1] 侯桂玉[1] 王桂莲[1] 罗健敏[1] 

机构地区：[1]顺德区第一人民医院,广东佛山528300

出　　处：《现代医院》2012年第7期63-64,共2页Modern Hospitals

摘　　要：目的探讨围生期颅内静脉窦血栓形成(CVST)的高危因素、临床特点、治疗及其预防措施。方法回顾性分析15例围生期CVST的临床资料。结果发生于妊娠期11例,产后4例。头痛4例,抽搐发作10例,意识障碍1例。发病后行多层螺旋CT(MSCT)、磁共振成像(MRI)及磁共振静脉血管造影(MRV)、磁共振动脉血管造影(MRA)而确诊。均用抗凝及溶栓治疗。痊愈10例,存留功能障碍4例,死亡1例。结论 CVST高危因素主要有重度子痫前期或子痫、剖宫产术、长期卧床、不规律产检。围生期CVST首发症状以头痛和抽搐为主。对于有危险因素的孕产妇应警惕CVST的可能。MRI和MRV为主要的诊断方法。全身抗凝及溶栓治疗有较好疗效。Objective To investigate the risk factors, clinical features, treatment and prophylaxis of patients with perinatal cerebral venous sinus thrombosis （CVST）. Methods A retrospective study was performed in 15 eases of perinatal women with CVST. Results 11 cases occurred in the gestational period, and the other 4 eases in the puerperium. The clinical manifestation were headache in 6 cases, convulsion in 10 cases, disturbance of consciousness in one cases. All cases were diagnosed by multislice spiral computed tomography （MSCT） , magnetic resonance ima- ging （MRI） ,magnetic resonance venous angiography （MRV）and magnetic resonance arterial angiography （MRA）. Anticoagulant and thrombolytic therapy were adopted in all cases. 10 cases were fully recovered. 4 left with dysfunction. 1 died. Conclusion Severe preeclampsia or eclampsia, cesarean section, long- term keeping in bed, irregular Prenatal care are the capital risk factors of CVST. Headache and convulsions were the first symptoms of perinatal CVST. The possibility of CVST should be considered in the perinatal women with risk factors. MRI and MRV are the main diagnostic methods.

关 键 词：围生期 颅内静脉窦血栓形成 

分 类 号：R743.32[医药卫生—神经病学与精神病学]