老年急性白血病37例临床分析  

Clinical analysis on 37 cases of acute myeloid leukemia in elderly patients

作　　者：张建瑜[1] 李婷[1] 罗冰[1] 

机构地区：[1]广州医学院第三附属医院血液内科,510150

出　　处：《国际医药卫生导报》2012年第14期2098-2099,共2页International Medicine and Health Guidance News

摘　　要：目的分析老年急性白血病临床特点，化疗方案及预后疗效等。方法对2003年至2010年间初治老年急性白血病37例进行分析，中位年龄71（60—93岁），男16例，女21例。急性淋巴细胞白血病（ALL）5例；急性非淋巴细胞白血病（AML）32例，以M2（40．6％）为主。26例患者接受联合化疗，治疗予NA、TA及NAOP方案进行联合化疗。结果完全缓解率26．9％，2年存活率11．5％，死亡率81％。结论老年急性白血病总体缓解率低，死亡率高，化疗耐受性差。Objective To analyze the clinic characteristics, treatment and prognosis of acute leukemia in elderly patients. Methods 37 cases of acute leukemia who were older than 60 years from Jan, 2003 to Jan, 2010 were studied retrospectively. The median age was 71 （ranging from 60 to 93）, including 16 male cases and 21 female cases. Among them, 5 cases were acute lymphocytic leukemia （ALL） and 32 cases were non-lymphocytic leukemia （ANLL）. 26 patients received chemotherapy such as NA, TA and NAOP. Results Complete remission （CR） rate was 26.9%, 2 years of survival rate was 11.5%, and mortality was 81%. Conclusion The CR rate of acute leukemia in elderly is low and mortality rate is high. Supportive treatment such as infection prevention should be emphasized during chemotherapy.

关 键 词：白血病 急性 老年人 化疗 

分 类 号：R733.71[医药卫生—肿瘤]