阿普唑仑联合氟桂利嗪治疗老年人功能性消化不良疗效观察  

Therapeutic effect of alprazolam combined with flunarizine on functional dyspepsia of the elderly

作　　者：马文青[1] 张南征[1] 朱云[1] 

机构地区：[1]中国人民解放军第九七医院消化内科,江苏徐州221004

出　　处：《徐州医学院学报》2012年第6期390-392,共3页Acta Academiae Medicinae Xuzhou

摘　　要：目的观察阿普唑仑及氟桂利嗪在治疗老年人功能性消化不良中的治疗效果。方法160例患者随机分成4组（每组40例）：A组（对照组），予以常规治疗（奥美拉唑、多潘立酮）；B组，予以常规治疗联合阿普唑仑治疗；C组，予以常规治疗联合氟桂利嗪治疗；D组，予以常规治疗联合阿普唑仑并氟桂利嗪治疗。观察各组患者治疗效果。结果A组有效率40．00％，B组有效率60．00％，C组有效率52．25％，D组有效率82．5％。D组较A、B、C组治疗有效率显著提高，B、C组治疗有效率显著高于A组，差异有统计学意义（P〈0．01），B、C组之间疗效无显著差异。结论阿普唑仑和氟桂利嗪治疗老年人功能性消化不良有效，二者联合可提高治疗效果。Objective To evaluate the therapeutic effect of alprazolam and flunarizine on functional dyspepsia（FD） of the elderly. Methods 160 FD patients were randomized into 4 groups （n = 40 each ） ： group A, routine regimen （omeprazole plus domperidone） as the control; group B： routine regimen combined with alprazolam; group C： routine regimen combined with flunarizine; group D： routine regimen combined with alprazolam and flunarizine. The efficacy in each group was observed and compared. Results The efficacy rate was 40.00% in group A , 60.00% in group B, 52.25% in group C, and 82.50% in group D. The efficacy rate in group D was significantly higher than group A, B and C, the efficacy rate in group B and C was significantly higher than in group A, with statistical differences （P 〈 0.01 ）, while there was no significant difference between group B and C. Conclusion Both alprazolam and flunarizine were effective in treating FD of the elderly. Moreover, the therapeutic effect would be improved dramatically when combing

关 键 词：阿普唑仑 老年人 功能性消化不良 氟桂利嗪 

分 类 号：R574.4[医药卫生—消化系统]