针灸结合尼莫地平治疗轻度认知功能障碍的疗效研究  

Efficacy of Acupuncture Combined with Nimodipine in the Treatment of Mild Cognitive Impairment

作　　者：赵延红[1] 

机构地区：[1]广东省佛山市第二人民医院神经内科,528000

出　　处：《临床合理用药杂志》2012年第21期16-17,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的观察针灸结合尼莫地平治疗轻度认知功能障碍的疗效。方法将我院收治的60例轻度功能障碍患者随机均分为两组:对照组给予尼莫地平治疗;观察组给予针灸结合尼莫地平联合治疗,疗程均为8周。两组治疗后比较观察精神状态简易速表(MMSE)、蒙特利尔认知量表(MoCA)及事件相关电位(ERP)等变化。结果两组患者的MMSE和MoCA在治疗前后差异具有统计学意义(P<0.05),观察组疗效明显优于对照组;两组患者的ERP的潜伏期及波幅在治疗前后差异具有统计学意义(P<0.05),观察组的疗效优于对照组。结论针灸结合尼莫地平治疗轻度认知功能障碍疗效优于尼莫地平。Objective To observe the efficacy of acupuncture combined with Nimodipine in the treatment of mild cog- nitive impairment. Methods 60 cases of MCI admitted in our hospital were randomly divided into two groups： control group was given the treatment of Nimodipine for eight weeks; while observation group was treated with acupuncture combined with Nimodip- ine for eight weeks. After the treatment, mental state of simple speed table （ MMSE）, Montreal Cognitive Scale （MoCA） and e- vent - related potentials （ERP） were observed and analyzed. Results MMSE and MoCA were statistically significant before and after the treatment （ P 〈0, 05 ） ; latency and amplitude of ERP were statistically significant （ P 〈 0. 05 ）, observation group was better than control group. Conclusion The treatment of Acupuncture combined with Nimodipine is more effective than the treat- ment of Nimodipine.

关 键 词：针灸 尼莫地平 认知障碍 治疗结果 

分 类 号：R749.1[医药卫生—神经病学与精神病学] R246.6[医药卫生—临床医学]