舒洛地特治疗非糖尿病性慢性肾脏病的疗效观察  

Effects of Sulodexide in the treatment of patients with chronic kidney disease

作　　者：秦建华[1] 吴蔚桦[1] 张帆[1] 彭波[1] 

机构地区：[1]四川省泸州医学院附属医院肾内科,泸州646000

出　　处：《临床肾脏病杂志》2012年第7期320-322,共3页Journal Of Clinical Nephrology

摘　　要：目的观察舒洛地特治疗非糖尿病性慢性肾脏病（CKD）2～3期的临床疗效及安全性。方法将40例非糖尿病性CKD2～3期患者随机分为对照组和治疗组，每组20例。对照组进行常规治疗（包括降压、肠道排毒及纠正贫血等处理）；治疗组在对照组治疗的基础上加服舒洛地特胶囊25mg／次，2次／d，共50d。比较2组治疗后血肌酐、24h尿蛋白定量及纤维蛋白原含量。结果治疗组血肌酐、24h尿蛋白定量及纤维蛋白原含量明显低于对照组（P〈0．05）。结论舒洛地特治疗非糖尿病性CKD2～3期效果好，具有临床应用价值。Objective To observe the effects of Sulodexide in the treatment of chronic kidney disease （CKD）. Methods Forty patients with CKD were randomly divided into control group（routine treatment） and Sulodexide-treated group（routine treatment ＋ Sulodexide）. Results The serum creatinine, 24-4 urine protein secretion and fibrinogen in Sulodexide-treated group were significantly decreased as compared with those in control group（P〈0. 05）. Conclusions Sulodexide is effective in the treatment of CKD.

关 键 词：肾衰竭 慢性 舒洛地特 治疗效果 

分 类 号：R743.330.2[医药卫生—神经病学与精神病学]