零球差非球面人工晶状体在高度近视眼中对比度视力与像差的研究  

Contrast visual acuity and wavefront after implantation of a zero spherical aberration intraocular lens in high myopia

作　　者：朱双倩[1] 薛安全[1] 俞阿勇[1] 苏炎峰[1] 郑林燕[1] 王勤美[1] 

机构地区：[1]温州医学院附属眼视光医院,温州325027

出　　处：《中国实用眼科杂志》2012年第8期917-920,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的研究高度近视患者晶状体摘除联合零球差非球面与球面人工晶状体植入术后暗环境对比度视力及波前像差差异。方法在本前瞻性队列研究中，选择28例（44只眼）高度近视患者，按植入的人工晶状体类型分成2组，试验组23只眼，植入零球差非球面人工晶状体Akreos AO（Bausch＆Lomb，Inc），对照组21只眼，植入球面人工晶状体（Rayner Superflex^TM 620H）；于手术术后3个月时测量最佳矫正视力，角膜像差，全眼像差及暗环境下对比度视力。结果（1）试验组与对照组各参数比较；年龄[（52．6±5．7）岁vs．（54．1±5．9）岁，P=0．281）]、眼轴长度[（30．21±2．06）mm vs．（31．03±2．03）mm，P=0．289]、手术前最佳矫正视力（4．68±0．10vs．4．63±0．12P=0．248）、人工晶状体度数[（4．8±2．98）Dvs（3．42±3．83）D，P=0．235]、术后等效球镜度数[（-2．53±1．25）Dvs（-2．12±0．70）D，P=0．273]手术后最佳矫正视力（4．83±0．15vs．4．76±0．15P=0．211）均无统计学意义（P〉0．05）。（2）像差比较（6mm瞳孔直径）：术后角膜球差[（0．27±0．18）μmvs（0．28±0．16）μm，P=0．905）]、全眼球差[（0．23±0．14）μmvs（0．32±0．16）μm，P=0．144）]、全眼总高阶像差[（1．46±0．48）μmvs（1．14±0．50）μm，P=0．277]、彗差[（0．68±0．45）μmvs（0．73±0．48）μm，P：0．782]、三叶草[（0．55±0．15）μmvs（0．42±0．16）μm，P=0．377）]差异均无统计学意义（P〉0．05）。（3）暗环境下对比度视力：100％对比度视力（0．16±0．19vs．0．19±0．17P=0．64）25％对比度视力（0．39±0．20vs．0．47±0．22P=0．31）、10％对比度视力（0．65±0．29vs．0．78±0．31P=0．22）、5％对比度视力（0．90±0．24vs．0．99±0．27P：0．40）亦均无统计学意义（P〉0．05）。结论（1）零球差非球面低度数人工晶状体植入高�Objective To compare contrast visual acuity and wavefront aberrations in highly myopic eyes implanted with a zero spherical aberration intraocular lens （IOL） and a spherical IOL. Methods A prospective case-controlled study was designed. Twenty-eight high myopia patients were randomized to receive 2 IOL types： Akreos AO （23 eyes）, and Rayner Superflex ,M 620H （21 eyes）. Complete ophthalmologic examination including best-spectacle corrected visual acuity （BSCVA）, Contrast Visual Acuity, and wavefront aberration of the cornea and eye were performed 3 months postoperatively. Results The zero spherical aberration IOL group and the spherical IOL group did not differ in baseline characteristics, including age （52.6±5.7 yrs vs 54.1± 5.9 yrs, P =0.281）, axial length （30.21±2.06mm vs 31.03±2.03mm, P =0.289）, Pre-BSCVA （4.68±0.10 vs.4.63±0.12, P =0.248）, IOL power （4.88±2.98D vs. 3.42±3.83D, P =0.235）, Postoperative spherical equivalent refraction （-2.53±1.25D vs. -2.12±0.70D, P =0.273）, Post-BSCVA （4.83±0.15 vs.4.76±0.15, P =0.211）, and pupil size of 6mm： Postoperative corneal spherical aberration （0.27±0.18μm vs. 0.284-0.16μm, P =0.905）, total ocular spherical aberration （0.23±0.14μm vs. 0,32＋0.16μm, P =0.14）, total high-order aberration （1.46±0.48μm vs. 1.14±0.50μm, P =0.277）, coma aberration （0.68± 0.45μm vs. 0.73±0.48μm, P =0.782）, trefoil aberration （0.55±0.15μm vs. 0.42±0.16μm, P =0.377）, under the mesopic condition, 100% Contrast Visual Acuity （0.16±0.19 vs. 0.19±0.17, P =0.64）, 25% Contrast Visual Acuity （0.39±0.20 vs.0.47± 0.22, P =0.31）, 10% Contrast Visual Acuity （0.65±0.29 vs. 0.78±0.31, P =0.22）, 5% Contrast Visual Acuity （0.90±0.24 vs. 0.99±0.27, P =0.40）. Conclusions The spherical aberration is not considerably lower in the zero spherical aberration IOL group compared with spherical IOL group in high myopia. Under the mesopic condition different Contrast Visual Acuity, the zero spherical ab

关 键 词：高度近视 人工晶状体 非球面 波前像差 对比度视力 

分 类 号：R776.1[医药卫生—眼科]