三种方案治疗新生儿高胆红素血症的疗效比较  

Efficacy comparison of three therapy regimens in treatment of neonatal hyperbilirubinemia

作　　者：颜金花[1] 

机构地区：[1]四川省人民医院新生儿监护室,四川成都610072

出　　处：《现代医药卫生》2012年第13期1946-1947,共2页Journal of Modern Medicine & Health

摘　　要：目的探讨三种不同方案治疗新生儿高胆红素血症的疗效。方法随机选取新生儿高胆红素血症患儿210例,分为甲、乙、丙三组,例数分别为59、62、63例。甲组采用光疗联合清蛋白、金双歧(双歧杆菌乳杆菌三联活菌片)治疗,乙组采用光疗联合茵栀黄颗粒、金双歧治疗,丙组采用光疗联合清蛋白、茵栀黄颗粒、金双歧治疗,3 d后观察皮肤黏膜黄疸程度及血清胆红素的变化,结果采用χ2检验进行分析。结果甲、乙、丙组显效、有效、无效分别为35、13、11例,37、14、11例,46、13、4例,甲、乙组比较,总有效率差异无统计学意义(P>0.05),丙组与甲、乙组比较,总有效率差异有统计学意义(P<0.05)。结论丙组治疗方案优于甲、乙治疗方案,光疗联合清蛋白、茵栀黄颗粒、金双歧治疗方案对新生儿高胆红素血症效果良好。Objective To investigate the efficacy of three different therapy regimens in treating neonatal hyperbiliru- binemia. Methods 210 cases of neonatal jaundice were randomly selected and divided into the group A（59 cases） ,B（62 cases） and C（63 cases）. The group A used the phototherapy＋albumins＋Golden Bifid,the group B was treated with phototherapy＋ Yinzhihuang Granules＋Golden Bifid and the group C with phototherapy＋alhumins＋Golden Bifid＋Yinzhihuang Granules. After 3 d, the degrees of skin and mucosal jaundice and the change of serum bilirubin were observed and the results were analyzed by us- ing ）（2 test. Results The excellent effect, effect and ineffectiveness in the group A, B and C were 35,13 and 11 cases, 37,14 and 11 cases,46,13 and 4 cases respectively,without statistical differences among them （P〉0.05）. Comparing the group C with the group A and B,the total efffective rate had statistical difference （P〈0.05）. Conclusion The therapy regimen in the group C is better than that in the group A and B. The therapy regimen of phototherapy＋albumins＋Yinzhihuang Granules ＋Golden Bifid has better effect in treating neonatal hyperbilirubinemia.

关 键 词：高胆红素血症/治疗 婴儿 新生 疾病 光疗法 白蛋白类 二裂菌属 乳杆菌属 栀子/治疗应用 黄芩/治疗应用 茵陈/治疗应用 双歧杆菌乳杆菌三联活菌片 茵栀黄 

分 类 号：R722.17[医药卫生—儿科]